ID A0A067NHU4_PLEOS Unreviewed; 284 AA.
AC A0A067NHU4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=NAD(P)-binding domain-containing protein {ECO:0000259|Pfam:PF13460};
DE Flags: Fragment;
GN ORFNames=PLEOSDRAFT_1089325 {ECO:0000313|EMBL:KDQ27409.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ27409.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- PATHWAY: Alkaloid biosynthesis; ergot alkaloid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005107}.
CC -!- SIMILARITY: Belongs to the fgaFS/easG family.
CC {ECO:0000256|ARBA:ARBA00005372}.
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DR EMBL; KL198008; KDQ27409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067NHU4; -.
DR STRING; 1137138.A0A067NHU4; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1089325; -.
DR HOGENOM; CLU_007383_10_6_1; -.
DR InParanoid; A0A067NHU4; -.
DR OrthoDB; 1605083at2759; -.
DR UniPathway; UPA00327; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0035835; P:indole alkaloid biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR019901; Ergot_alkaloid_biosynthesis.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR03649; ergot_EASG; 1.
DR PANTHER; PTHR43162; -; 1.
DR PANTHER; PTHR43162:SF1; PRESTALK A DIFFERENTIATION PROTEIN A; 1.
DR Pfam; PF13460; NAD_binding_10; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Alkaloid metabolism {ECO:0000256|ARBA:ARBA00022589};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073}.
FT DOMAIN 7..182
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF13460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KDQ27409.1"
SQ SEQUENCE 284 AA; 30961 MW; 6A0F66D8C13DAACE CRC64;
MAILITGGTG KTGSRLARQL HEHGLTAYIT SRSPGTVPAP HKGVKFDWSD TSTFENPFKA
AADANDHIDG VYLVSPNFPD MAAVAASFID LAVKHGVKRF VLLSATQLNK GDIMMGAIHE
YLDKKGLDYC VLRPSWFQEN FLMPEYLSLI VKENIIVSAA GDGRVPWISA DDIAATAVKA
FTAETIEQRD LYVVGPELLS YDDVAALFTD ILGRRITHKR VSEAELKEDF IAFGLAEPIA
TALAFLNTVI ASGGEEAVTK AENKYVGKQR LRDLVEANKS SWSN
//
