ID A0A067NPE1_PLEOS Unreviewed; 1160 AA.
AC A0A067NPE1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=PIN domain-containing protein {ECO:0000259|SMART:SM00670};
GN ORFNames=PLEOSDRAFT_1075740 {ECO:0000313|EMBL:KDQ28840.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ28840.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
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DR EMBL; KL198007; KDQ28840.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067NPE1; -.
DR STRING; 1137138.A0A067NPE1; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1075740; -.
DR HOGENOM; CLU_003327_0_0_1; -.
DR InParanoid; A0A067NPE1; -.
DR OrthoDB; 2516823at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:UniProt.
DR CDD; cd09880; PIN_Smg5-6-like; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR018834; DNA/RNA-bd_Est1-type.
DR InterPro; IPR045153; Est1/Ebs1-like.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR15696:SF39; EST_SMG-LIKE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR15696; SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7; 1.
DR Pfam; PF10373; EST1_DNA_bind; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000027073}.
FT DOMAIN 985..1137
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
FT REGION 1..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 952..975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..673
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..932
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1160 AA; 130409 MW; D9E7FB9EA7285747 CRC64;
MSAVPDVQRP SRKGKERDQA NFDFAENFQD KLIAFRRNAA GPPRPKERQQ MPALQHSAPQ
PSPASPSKPS SSRSKPSNHS PPSPRKLHPI TQHHPSRSSP GEADLEDFSR LRISSPPNTR
PSPTHRHVGP SKLFNPDTDP IPMRRTAEPE SISDATSSSY APRREVNGTS TAAQSSHHLR
DGPPRQLFDH RKDDPVRFSV LSRPNGRPTP TPKSSGEYVS ASSASSYAAS TLSSSFTLSS
DTTSGSSASA LFDNRSKPSS DSSTNNKFAL QLKGLYRNIT ELETQIKKDD ATDDSNESNT
RIMLQGKETT DEQFERERWR KQIADHKMLA EMMHNLLEIS LAPTVPASLR NIPVKYNIIV
RLWSYGFHKL LESLRRASFT SPLALEHLQD FIYYAYTFYT GLYEEQTLIS FKSGWLEALG
DLARYQMIVA TMVQSNFGHG ALLTTDALSR VPADNADKEE TSGLEDTHSD SDIRHQEPSV
GVAAARLMEV EPEKERWRKI AQGWYGKGIA DTPGNGRLHH HLGLLSREAE GEELRAVYHF
VKSMTTLHPF LTSRETILPV WSIALQARRS LPEARAPDLF VLLHGMLFTN IELDNFQPTL
ARFLERLAIE GAEDKEWIMM AVVNIGAVLE YGKPGGVLKK AGAIGGKDVS GTTTRVMTKD
REHDKDRMDI DDAPSHPTPP SSEAEAEIVT PVVFSLALQL TFAMLSHVLR NPIRGDTMNP
YLTVLMTFLA TILKEEKALK ILERNIPWAE LAKFFSGIPS RIMKKQQLDQ VVTHGERWVM
LSSKCTPLRE DWCLRAMEWV GRKIFERGYW PKEDDRQAEL ELLDERLKDT DGHIEDDTGR
EETLVDDRWT RIARCAVGIA NVVDGFTWVE GTRQWLVEGL LAQKVRGWQE LDRIEREEEE
RRRMGRRWDD SMDIDDEPAY EESSDEDDEN DSEEVKALKA RRKYLQSLIQ ATSQTTISPP
RHPRSNKANK AANGRPPLSI LPGYTILVVD TNILLSSLPL LTPVIESLRW TVVIPLPVIM
ELDGLATNMS TLGQAARDAL EYVTSHIRTH SISLKVQTSK GNYLTSLNVR TEQVDFVDNM
TGSLAERSMD DLILKAAIWQ DEHWIDRTSM LKVELKSEDI SAAVKVVLIT LDRNLRLKAR
SRSLPAANEK ELASIFATAT
//
