ID A0A067PRF7_9AGAM Unreviewed; 1008 AA.
AC A0A067PRF7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Antiviral helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=JAAARDRAFT_138149 {ECO:0000313|EMBL:KDQ52896.1};
OS Jaapia argillacea MUCL 33604.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Jaapiales; Jaapiaceae; Jaapia.
OX NCBI_TaxID=933084 {ECO:0000313|EMBL:KDQ52896.1, ECO:0000313|Proteomes:UP000027265};
RN [1] {ECO:0000313|Proteomes:UP000027265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUCL 33604 {ECO:0000313|Proteomes:UP000027265};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
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DR EMBL; KL197737; KDQ52896.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067PRF7; -.
DR STRING; 933084.A0A067PRF7; -.
DR HOGENOM; CLU_002902_0_1_1; -.
DR InParanoid; A0A067PRF7; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000027265; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd13154; KOW_Mtr4; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000027265}.
FT DOMAIN 83..239
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 322..526
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 287..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 789..816
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 662..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 113880 MW; ECF319EEABA4B6FE CRC64;
MASPKPIVVD EVEIEAKREV AASAGLTGAA VESGSRLELK HQVRHQVAVP SGYNYIPIAN
HIPPAKPARE YKFTLDPFQQ VSVNAIQRNE SVLVSAHTSA GKTVVAEYAI AQCLLNKQRV
IYTSPIKALS NQKYREMLAE FGDVGLMTGD VTINPSATCL VMTTEILRSM LYRGSEIMRE
VAWVIFDEIH YMRDKERGVV WEETIILLPH TVRYVFLSAT IPNAMQFAEW ICKSHEQPCH
IVYTNFRPTP LQHYLFPAGG EGIYLVVNEK GEFREDNFTK AMGMLQDKAG EDPADPKSGK
GRKGKSKKGG DKKAFDPVGP SDIQKIIKMI MLKNYNPVIV FAFSKRECEA LALAMSKFEF
NTADEQDLIT NIFNNAMDNL APADRQLPQI SNLLPLLKRG IGIHHGGLLP ILKEVIEILF
QEGLIKALFA TETFSIGLNM PAKTVVFTAA RKFDGREFRN LSSGEYIQMS GRAGRRGLDD
RGVVIMMCDE KLEPSAAMNM VKGEADRLDS AFHLGYNMVL NLMKVEGISP EFMLERCFFQ
FQNSAGVPML EDELRKEEEF KDSIIIPDEA LVAEYYDYRQ QLDQMASDFR DVITHPNYSL
PFLQPGRLVK VKHQDMDFGW GVIISYQKRV PPKNRPMPQT EEIPPHEQYV LDVLLNCSTG
SMLPKERNSS STSATPGGVL PCPSGQKGDP LVVPVLLSTI DSISHIRIFL PKDLRQSQAR
ETVWKSVLEV QKRFPDGIAL LDPVQNMGIK DDKFQMLIKK IDMMEKKMFS SPLHKDPRLP
EIYTLYSRKQ ERQQRIRALK KRIQATNDVL QMEELKCRKR VLRRLGFTTA DDIVDVKGRV
ACEISTGDEL LLTELIFNGV FNPLSPEQCA GLLSCFVFTE KSEQVTKLKE ELAAPLRVMQ
EVARRIAKVS KESKLPIDED EYVSSFKVEL MDAVVQWCRG ASFSDICKLT DQFEGSLIRV
FRRLQELIRQ MSQAAKVIGN TELQEKFEKA SEMLERPNSV IFCSSLYL
//
