ID A0A067Q854_9AGAM Unreviewed; 836 AA.
AC A0A067Q854;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 28-JUN-2023, entry version 22.
DE RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN ORFNames=JAAARDRAFT_33251 {ECO:0000313|EMBL:KDQ59677.1};
OS Jaapia argillacea MUCL 33604.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Jaapiales; Jaapiaceae; Jaapia.
OX NCBI_TaxID=933084 {ECO:0000313|EMBL:KDQ59677.1, ECO:0000313|Proteomes:UP000027265};
RN [1] {ECO:0000313|Proteomes:UP000027265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MUCL 33604 {ECO:0000313|Proteomes:UP000027265};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC multimeric enzyme that catalyzes the translocation of protons across
CC the membranes. Required for assembly and activity of the V-ATPase.
CC {ECO:0000256|RuleBase:RU361189}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR EMBL; KL197715; KDQ59677.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067Q854; -.
DR STRING; 933084.A0A067Q854; -.
DR HOGENOM; CLU_005230_0_0_1; -.
DR InParanoid; A0A067Q854; -.
DR OrthoDB; 1967517at2759; -.
DR Proteomes; UP000027265; Unassembled WGS sequence.
DR GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR InterPro; IPR002490; V-ATPase_116kDa_su.
DR InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR Pfam; PF01496; V_ATPase_I; 1.
DR PIRSF; PIRSF001293; ATP6V0A1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW ECO:0000256|RuleBase:RU361189};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU361189};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW Reference proteome {ECO:0000313|Proteomes:UP000027265};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361189};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361189};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT TRANSMEM 423..448
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 460..485
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 548..569
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 581..603
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 643..661
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT TRANSMEM 773..797
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361189"
FT COILED 105..146
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 836 AA; 94688 MW; FEA711FCFE834262 CRC64;
MGDDYPSPFR SEQMSLVQLF IPTEVAHDAV AELGELGNVE FKDLNPNVNP FQRSFVGEIR
RIDEMARRVR FFASQIEKEK DVVPIRPLYD SAPLITVGPR AAQTIDELDV KLTEHEARLT
QMNESYETLS ERMRELIEAK HVLRETAVFF ERAQTHETDI RTSFDESSAP LLQHADRENQ
YSSTSVQFDL EFVAGTIDRA RLQTFERVLW RVLRGNLYMN YTDIPEPFVN PSTGEETRKN
VFIIFAHGST LLSKIRKVSE SMGATLYPID SNADKRADSL REVMGRLEDL QAVLYNTGVS
RRGELVVIGE GLRGWEDVVR KEKMIYTTMN LFEYDVRRKT LLAEGWCPSR DITTIQLALR
HATEESGTSV PPILHELRTH KTPPTFIRTN KFTEGFQTIM DSYGIASYEE VNPGLFATIT
FPFLFAVMFG DIGHGAIVFT AAMGMILFER KLAASDLGEI FGTFFFGRYI ILLMGLFSMY
TGLIYNDIFS KSLHIWHSGW SWPEAPGGNS TDTIAAFSNG HTYPFGLDPG WHGAENGLVF
TNSYKMKMSI VLGVIHMTFA LCLQVPNHIR FKRYSDIWTN FIPQMIFLQS IFGYLVLCIL
YKWSIDWTTS PTSPPSLLTM LIAMFLTPGT VDPETQLYAG QSFVQTVLLG AAGICVPWLL
ITKPYLQWRE MKKIQGQGYV GIHADGDHAD EVLEGEEEGN GRAIVESMDE EHEQHDFSEV
IVHQVIHTIE FCLGCISHTA SYLRLWALSL AHAQLSEVLW TMTLEKVLGM EGILGMIALV
LVFALWLNLT ISILCIMEGL SAFLHALRLH WVEANSKHYE AGGRQFMPLS FAKADE
//
