ID   A0A067QJN8_ZOONE        Unreviewed;      1294 AA.
AC   A0A067QJN8;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Cytoplasmic FMR1-interacting protein {ECO:0000256|PIRNR:PIRNR008153};
GN   ORFNames=L798_01158 {ECO:0000313|EMBL:KDR09197.1};
OS   Zootermopsis nevadensis (Dampwood termite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC   Termopsidae; Zootermopsis.
OX   NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR09197.1, ECO:0000313|Proteomes:UP000027135};
RN   [1] {ECO:0000313|EMBL:KDR09197.1, ECO:0000313|Proteomes:UP000027135}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole organism {ECO:0000313|EMBL:KDR09197.1};
RX   PubMed=24845553; DOI=10.1038/ncomms4636;
RA   Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA   Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA   Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA   Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA   Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA   Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA   Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA   Liebig J.;
RT   "Molecular traces of alternative social organization in a termite genome.";
RL   Nat. Commun. 5:3636-3636(2014).
CC   -!- SIMILARITY: Belongs to the CYFIP family.
CC       {ECO:0000256|ARBA:ARBA00025790, ECO:0000256|PIRNR:PIRNR008153}.
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DR   EMBL; KK853265; KDR09197.1; -; Genomic_DNA.
DR   STRING; 136037.A0A067QJN8; -.
DR   EnsemblMetazoa; KDR09197; KDR09197; L798_01158.
DR   eggNOG; KOG3534; Eukaryota.
DR   InParanoid; A0A067QJN8; -.
DR   OMA; DQPNRVE; -.
DR   OrthoDB; 446059at2759; -.
DR   Proteomes; UP000027135; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR   InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR   InterPro; IPR008081; Cytoplasmic_FMR1-int.
DR   PANTHER; PTHR12195:SF0; CYTOPLASMIC FMR1-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR12195; CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED; 1.
DR   Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
DR   Pfam; PF05994; FragX_IP; 1.
DR   PIRSF; PIRSF008153; FMR1_interacting; 1.
DR   PRINTS; PR01698; CYTOFMRPINTP.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR008153};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027135}.
FT   DOMAIN          67..281
FT                   /note="CYRIA/CYRIB Rac1 binding"
FT                   /evidence="ECO:0000259|Pfam:PF07159"
SQ   SEQUENCE   1294 AA;  149825 MW;  BB6BEBB5B8B6297C CRC64;
     MQSSTMATEK VTLTDALSNV DVLDELTLPD EQPCIEAQPC SVVYQANFDT NFEDRNGFVT
     GIAKYIEEAT VHASLNELLE EGLVHAVMLY TWRCCSRAIP QPKSNEQPNR VEIYEKTVEV
     LAPEVNKLLN FMYFQRKAIE RFSAEVKRLC HQEKRKDFVS EAYLLTLGKF INMFAVLDEL
     KNMKSSVKND YSTYRRAAQF LKVMADSQTL QESQNLSMFL ATQNKIRDTV KENLEKIPGY
     EELLADVVNI CVHMFETKMY LTPTEKHMLV KVMGFGLFLM DSELCNINKL DQKKKLKLEK
     IDRIFKNLEV VPLFGDMQIA PFNYIKRSKH FDPSKWPLSS SNSISPQADL MVHLPQIRED
     HVKYISELAR YSNEVTTTYK ETRSDAENKE TADLALRGLQ LLSEWTSVVT ELYSWKLLHP
     TDHHQNKDCP QEAEEYERAT RYNYTDEEKF ALIEVIAMIK GLQVLMARME TVFTDAIRRN
     IYAELQDFIQ LLLREPLRKA IKNKKDLIRS IIVSVRETCA DWQRGVEPQA DPALKGKKDP
     DNGFGIKVPR RNVGPSSTQL YMVRTMLESL IADKSGGKRT LRKDIDGQYL VQIDQFHKTS
     FYWNYMLAFS ASLQDCCDLS QLWYREFYLE MTMGRRIQKC TVRHQHNEEC SDLITMEKRI
     QFPIEMSMPW ILTDHILRTK EPSMMEYVLY PLDLYNDSAV YALTVFRKQF LYDEVEAEVN
     LCFDQFVYKL SEQIFAHYKQ LAASILLDKR FRVECVALGT YLLPYPRANR YETLLKQRHV
     QLLGRSIDLN KLITQRINAD MQKSLDLAVS KFEAGDITGI VELDGLLQVN RLCHKLLSKH
     LALDDYDAMF REANHNVLAP YGRITLHVFW ELNYDFLPNY CYNAATNRFV KCRGITFTQP
     VHRDKPPQMG HHYLWGSKQL NLAYSTIYGQ YAGFVGATHF RTMCRLLGYQ GIAVVMEELL
     KIVKSLVQGN LLQFTKTLME AMPKICKLPR YDYGSPGVLG YYHAQLNDIV QYPDARTELF
     HSFREFGNTI LFCLLMEQAL SQEEVCDLLH AAPFQNILPR PYCKDGEKPE TKQKRLEAKY
     AALQIVPNIE KLGTPKQAMI AREGDLLTRE RLCCGLSIFE VVLSRLRSFL DDPIWVGPPP
     ANGVLNVDEC TEFHRLWSAL QFVYCIPVGD TEFTVEELFG EGLNWAGCTM IVLLGQQRRF
     EALDFCYHIL RVQRVDGKDE NVKGIALKRM VDRIRRFQVL NSQIFAVLNK FLKSSDSDVM
     AVEHVRCFPP PLHPTLAAQA HYYRPEHLRQ AVPH
//