ID A0A067QSB9_ZOONE Unreviewed; 768 AA.
AC A0A067QSB9;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Spondin-1 {ECO:0000256|ARBA:ARBA00019594};
DE AltName: Full=F-spondin {ECO:0000256|ARBA:ARBA00030964};
GN ORFNames=L798_13753 {ECO:0000313|EMBL:KDR12501.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR12501.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR12501.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR12501.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR EMBL; KK853014; KDR12501.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067QSB9; -.
DR STRING; 136037.A0A067QSB9; -.
DR EnsemblMetazoa; KDR12501; KDR12501; L798_13753.
DR eggNOG; KOG3539; Eukaryota.
DR InParanoid; A0A067QSB9; -.
DR OMA; KVQHFTH; -.
DR OrthoDB; 5404502at2759; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd08544; Reeler; 1.
DR Gene3D; 2.60.40.2130; F-spondin domain; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR Gene3D; 2.60.40.4060; Reeler domain; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 4.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR002861; Reeler_dom.
DR InterPro; IPR042307; Reeler_sf.
DR InterPro; IPR009465; Spondin_N.
DR InterPro; IPR038678; Spondin_N_sf.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR044004; TSP1_spondin_dom.
DR NCBIfam; NF038123; NF038123_dom; 1.
DR PANTHER; PTHR11311; SPONDIN; 1.
DR PANTHER; PTHR11311:SF23; SPONDIN-1; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF02014; Reeler; 1.
DR Pfam; PF06468; Spond_N; 1.
DR Pfam; PF19028; TSP1_spondin; 1.
DR Pfam; PF00090; TSP_1; 3.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SMART; SM00209; TSP1; 4.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 4.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS51019; REELIN; 1.
DR PROSITE; PS51020; SPONDIN; 1.
DR PROSITE; PS50092; TSP1; 4.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000027135};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..768
FT /note="Spondin-1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011955078"
FT DOMAIN 1..179
FT /note="Reelin"
FT /evidence="ECO:0000259|PROSITE:PS51019"
FT DOMAIN 180..370
FT /note="Spondin"
FT /evidence="ECO:0000259|PROSITE:PS51020"
FT DOMAIN 631..681
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 768 AA; 85866 MW; FF1FAA80B0FF1A45 CRC64;
MWWVLWVCLL GTAHACVREP REEHSTALRS PGDNGFHIQV SGEPERYVPG AVYTLSLVGS
RTHGRLQQFT RFMLGVEPLD PHHGVVLGSD ASPQRVGSFQ LFGDSLTTFN EHCINTISEA
DDLPKTEIQV MWISPPKGSG CIIFRAMVLE DADNWYADDG ALSRKLCELV ESDKGRKSED
EEECCACDEA KYELIFEGLW SNHTHPKDFP FSLWLTHFSD VIGASHERNY SFWGEGQLAS
DGLRQVAEWG SVRGMEAELR AKSKHLRTLI KAAGLWYPRV NTNSTSTFRV DQRHPLVSVV
SMLGPTPDWI VGVPGLNLCN KDCTWIEQKI VDLYPWDAGT DSGISYMSPN SPTVPQEKIH
RITTLYPEDP RAPFYDPSGK PMLPLARLFL RRDSVIPKGC DEQSLDRILE EAVEVAENTE
DTSRPECGVT EYSEWSACSV TCGKGLRMRQ RNYLNQAKAG MMGCDRQLVS KEMCVADIPE
CAGGPVADND QQPLEDNEGI CTTTSWGPWS ECSVTCGIGT STRTRKFVER LGRKKCPHVS
IIEREKCMQP PCRGEDANHE VADPMCPVTE WSDWSPCSAS CGKGVKLRTR LLLVAPELQE
KCSARVELVQ QRHCIVQEDC TFDMVIAKQV CMMEQEVGPC QGYFERWYFE PRKGMCVPFG
YGGCRGNRNN FLTAKECNDA CAVVRDQLLQ QGAPQVQGLS SNVVVTAAPP PVDCMVSDWS
VWTDCSVTCG TGIRERFRMI KVKAENGGRP CPKRLVRRKK CQMGPCEI
//
