ID A0A067QSQ1_ZOONE Unreviewed; 877 AA.
AC A0A067QSQ1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Epidermal growth factor receptor kinase substrate 8 {ECO:0000313|EMBL:KDR08458.1};
DE Flags: Fragment;
GN ORFNames=L798_01214 {ECO:0000313|EMBL:KDR08458.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR08458.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR08458.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR08458.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- SIMILARITY: Belongs to the EPS8 family.
CC {ECO:0000256|ARBA:ARBA00006197}.
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DR EMBL; KK853326; KDR08458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067QSQ1; -.
DR STRING; 136037.A0A067QSQ1; -.
DR EnsemblMetazoa; KDR08458; KDR08458; L798_01214.
DR eggNOG; KOG3557; Eukaryota.
DR InParanoid; A0A067QSQ1; -.
DR OMA; SEKYTIH; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01210; PTB_EPS8; 1.
DR CDD; cd11764; SH3_Eps8; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR039801; EPS8-like.
DR InterPro; IPR033928; EPS8_PTB.
DR InterPro; IPR035462; Eps8_SH3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR013625; PTB.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041418; SAM_3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12287:SF23; AROUSER, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR12287; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN; 1.
DR Pfam; PF08416; PTB; 1.
DR Pfam; PF18016; SAM_3; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KDR08458.1};
KW Receptor {ECO:0000313|EMBL:KDR08458.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027135};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transferase {ECO:0000313|EMBL:KDR08458.1}.
FT DOMAIN 501..560
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 142..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..166
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..727
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KDR08458.1"
FT NON_TER 877
FT /evidence="ECO:0000313|EMBL:KDR08458.1"
SQ SEQUENCE 877 AA; 99165 MW; 710CEF2F859A0B19 CRC64;
TDGPQSSEEA PTYLMEHLAT FTVAKETGIV YPADGMRRLL QLEKSNGIWS QKMQLRLDMS
WVLIMDYETG AVMERFPVAL IQEPTAFTSH DPMEIYNNIL VFIVGDERAE RLGSRSEMHI
FQCQSISAQD LVEDLKLLRA GKAPARRRSR HIPPPPATPP PEPPGNGVNV REQVSVFNAA
AHRTGVVFPA HNRDDEVSST SSEKYERDVT ILNHCFDDIE KFIARLQHAA AASRELERRR
RNRKSKKKDL GDGMLTMRAK PPPELEFIDI FQKFKLSFNL LAKLKAHIHD PNAPELVHFL
FTPLALIVDA SHDTHYGPNL PAKVVSPLLT REAVNLLINC VTSKETELWH SLGDAWLIPR
DQWKGYVAPY HPVFLDGWSP EYPVADERER MSSPVGAGGT TAAVAAEGSR SRAEDVKRDD
SHYSSDYFEY ERREASPAAA GRYAYDNRNY GTRQDVYGRE ESARSDISAD SIERNGGAVG
MEGQQRFERS QASFLDDLRS RGAKIVQVTY PRTANNDKEL TVIRGEYLEV VDDSRKWWKA
RNWRGQVAHV PHTIVTPYQG GDPNDVFSNP LYAPPRGYDK HYPSQDPSRD ATEMSRPARS
PPIPPPAPAD WVRKERLGKK ASFPPVLCLF FCEESVSSCL TWSRRKRKFC RAPTRREEVQ
KGTNVNFISQ GLFSSTFSLF ILKWFLCACV MVENMYEDGL PTPRMRRNDA DSVSPPPPPP
PPADSTPVNP RSRSGTLLSR AHSSQDLHEE LKTVLTLFRD KKHNLDIVKT PEVFITQTSD
PAEVQNWLHA KGFRSLSDFR LRKQLHGMTG NELLSLTKSQ LEKHCGKDEG RRLDSQLTVQ
RNVSGYKTAR SSELRAILAR AREKAEDTGL DDDSKRQ
//
