ID A0A067QT48_ZOONE Unreviewed; 700 AA.
AC A0A067QT48;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
GN ORFNames=L798_01479 {ECO:0000313|EMBL:KDR08671.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR08671.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR08671.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR08671.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}.
CC -!- SIMILARITY: Belongs to the anoctamin family.
CC {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU280814}.
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DR EMBL; KK853309; KDR08671.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067QT48; -.
DR EnsemblMetazoa; KDR08671; KDR08671; L798_01479.
DR eggNOG; KOG2513; Eukaryota.
DR InParanoid; A0A067QT48; -.
DR OMA; YENHRTA; -.
DR OrthoDB; 534027at2759; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF74; ANOCTAMIN; 1.
DR Pfam; PF04547; Anoctamin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU280814};
KW Reference proteome {ECO:0000313|Proteomes:UP000027135};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU280814};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU280814}.
FT TRANSMEM 217..243
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 249..267
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 319..344
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 364..385
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 438..460
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT DOMAIN 209..664
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 700 AA; 81683 MW; D70AE221D7CB5302 CRC64;
MTKKRQPQSD GDMSASPNDS SEESAVVFPP TYIIVQFSKR IRATALVWLV NKVCSKRLDG
GAELLVRRQP HRDGEGVTLH VSASKIKFLE VAEELELKKR DRCGLIREFT VSQLDDFLED
GMHVDDLLTT AERQYIVRHE LENIRTLKED DQVPGYPAFR LYEGQSIVQM CLHWKLVKRM
YPLHDMEALD KLGKKWYWAL FQKQPFEDIR LYFGEAVALY FTFLGFYTTA LLVPMFLGFL
QLFLPTESIA FFCVFNVLWM TVFLEVWKRK CSELAFTWGT IGMTSLDEPR ANYRGVMGID
EVTGRYQPQF PRWKTNARLY CVSLPIVFVC MVGAFFVMLA SFWAEELLLN MKKQQSLEAG
EIVVLLPSII YSAVVFIMNS CYRKVATWLT EWENHRTQSQ FDRHRVTKLV LFEFVNNFMS
LFYIAFYVQD MDMLKNQLAV MLLIFQAINN FQEAILPLLI KYYNKRVTKA LKFDAILGNK
KTDESGRKKK SLSVNHEPSR AILDYIPELD SDDPRIELAI CEGEMEDYEG TYDDYLEMFI
QFGYVFLFSS VYPMAAFWAV ANNIMEIRAD AFKLCRLYRR PVAKRVKDTG AWQRAFEIVG
AMSIMTNCSL LCMSPQLRRL APTMTSVEWV LVFVVLEHML LGIRHFLHLV IPDRPEWVRV
ALARINHLSK RALKNERMLK SRRHILRRYK TVHGSHNYNS
//
