ID A0A067RRD7_ZOONE Unreviewed; 496 AA.
AC A0A067RRD7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Ataxin-10 {ECO:0000256|ARBA:ARBA00018804};
GN ORFNames=L798_15749 {ECO:0000313|EMBL:KDR23180.1};
OS Zootermopsis nevadensis (Dampwood termite).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Dictyoptera; Blattodea; Blattoidea; Termitoidae;
OC Termopsidae; Zootermopsis.
OX NCBI_TaxID=136037 {ECO:0000313|EMBL:KDR23180.1, ECO:0000313|Proteomes:UP000027135};
RN [1] {ECO:0000313|EMBL:KDR23180.1, ECO:0000313|Proteomes:UP000027135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole organism {ECO:0000313|EMBL:KDR23180.1};
RX PubMed=24845553; DOI=10.1038/ncomms4636;
RA Terrapon N., Li C., Robertson H.M., Ji L., Meng X., Booth W., Chen Z.,
RA Childers C.P., Glastad K.M., Gokhale K., Gowin J., Gronenberg W.,
RA Hermansen R.A., Hu H., Hunt B.G., Huylmans A.K., Khalil S.M.,
RA Mitchell R.D., Munoz-Torres M.C., Mustard J.A., Pan H., Reese J.T.,
RA Scharf M.E., Sun F., Vogel H., Xiao J., Yang W., Yang Z., Yang Z., Zhou J.,
RA Zhu J., Brent C.S., Elsik C.G., Goodisman M.A., Liberles D.A., Roe R.M.,
RA Vargo E.L., Vilcinskas A., Wang J., Bornberg-Bauer E., Korb J., Zhang G.,
RA Liebig J.;
RT "Molecular traces of alternative social organization in a termite genome.";
RL Nat. Commun. 5:3636-3636(2014).
CC -!- FUNCTION: Necessary for the survival of cerebellar neurons. Induces
CC neuritogenesis by activating the Ras-MAP kinase pathway. May play a
CC role in the maintenance of a critical intracellular glycosylation level
CC and homeostasis. {ECO:0000256|ARBA:ARBA00002116}.
CC -!- SIMILARITY: Belongs to the ataxin-10 family.
CC {ECO:0000256|ARBA:ARBA00008384}.
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DR EMBL; KK852471; KDR23180.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067RRD7; -.
DR STRING; 136037.A0A067RRD7; -.
DR EnsemblMetazoa; KDR23180; KDR23180; L798_15749.
DR eggNOG; KOG2676; Eukaryota.
DR InParanoid; A0A067RRD7; -.
DR OMA; CAWESPP; -.
DR OrthoDB; 5479391at2759; -.
DR Proteomes; UP000027135; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR019156; Ataxin-10_domain.
DR PANTHER; PTHR13255; ATAXIN-10; 1.
DR PANTHER; PTHR13255:SF0; ATAXIN-10; 1.
DR Pfam; PF09759; Atx10homo_assoc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000027135}.
FT DOMAIN 390..486
FT /note="Ataxin-10"
FT /evidence="ECO:0000259|Pfam:PF09759"
SQ SEQUENCE 496 AA; 55256 MW; 2746D8BD38272FD3 CRC64;
MASAKKFSNN LRAVTELEQE DDNYTDSLGV ENIFRCCELL TTFLRNKKWS EIGDTLTTIS
KALLKPENRK SVPLQALESL GIVLHVSAAE FKVDSPSVAA AVSETFRALR NSCVGEPKIQ
KDVTEKTVAV DETCNILKAL SLLPRNEHNV FCLRVGTQFL GNIVVNNKDT QPIVWRKCSE
VLIDLLKYED KKVANYSSMV IYNILLGHPD ISAAVENCKE ILEILIDHAM ADSEFALFTV
ELLLSRMGYL PKVYEKVAVT HRLFLLDAVH FMITADGDAR IPVTSITFLA SQFKVHSDCI
LKTCEKYVEG LEPAEVSKLL QLLASASANG NYRSELQKDT SLLITCSMLL CSMHNLGKMG
QNNFSAVQKL ADLSSFTQSS NIHEHPAFGF KSCLVQMLGN LCWRHPENQN QVRKLDCISV
LLDCCNIDAR NPLIIQWVVL AIRNLCENNL ENQAVIASMT RKGTVDSSVL LEMGLTLHAD
DESKIVIMPL DRKTSL
//
