ID   A0A067S6D7_GALM3        Unreviewed;       553 AA.
AC   A0A067S6D7;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=GALMADRAFT_1159461 {ECO:0000313|EMBL:KDR66386.1};
OS   Galerina marginata (strain CBS 339.88).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX   NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR66386.1, ECO:0000313|Proteomes:UP000027222};
RN   [1] {ECO:0000313|Proteomes:UP000027222}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX   PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA   Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA   Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA   LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA   Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA   Hibbett D.S., Grigoriev I.V.;
RT   "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT   white-rot/brown-rot paradigm for wood decay fungi.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   EMBL; KL142424; KDR66386.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067S6D7; -.
DR   STRING; 685588.A0A067S6D7; -.
DR   ESTHER; 9agar-a0a067s6d7; Fungal_carboxylesterase_lipase.
DR   HOGENOM; CLU_006586_10_6_1; -.
DR   OrthoDB; 2283588at2759; -.
DR   Proteomes; UP000027222; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027222}.
FT   DOMAIN          59..545
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   553 AA;  58338 MW;  20897238FAE04611 CRC64;
     MPAMQWDRLV SVISPVQPKP FTRVLEMVNQ TPLHKLALAL YAACCVLGSP AQTVATVDVT
     LKTGVFRGVT ASGGLEKFLG IPFAQPPVGN LRFKAPVAVT QGSSAIHDAS KFGNACAQPA
     NSGLGAPVAE SCLFLNVFRP QGVAANAKLP VLFWIHGGAF TTGAASSGSD PTEIIARSVA
     IGKPIIFVST NYRLNSFGFL ASASVPAGDL NAGLQDQRMA LAFVQDNIAA FGGDPTKVTI
     WGQSAGAGSV EAHLLFPPPR SLFRAAIGES STGPFKSSPN AATYDKPDKP FTRLLSATGC
     TAGKTAVSCL QKVPFATLQN ITNSMISATL NGQLWQPAVG PPGSFVPEES STRVASGNFL
     HIPYLGGTNL NEGTGFSGSV HGLKLSGTAE TDAFKNFIGH LVIDNSTLTN DVLNQIMTLF
     PANDPTLGGP FNTGDSLFDR SAAWYTDEMF LGPRRLFFQH GAALQPMFGY YFTEFIPGNS
     RTNGVSHGSE LQLIFGPVSS AAAQEIPLST AMRDFYINFV NDLNPGAAWP RYNPAAPQVA
     FINSPRVLGE FQK
//