ID A0A067SGU5_GALM3 Unreviewed; 2153 AA.
AC A0A067SGU5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=GALMADRAFT_258813 {ECO:0000313|EMBL:KDR66929.1};
OS Galerina marginata (strain CBS 339.88).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR66929.1, ECO:0000313|Proteomes:UP000027222};
RN [1] {ECO:0000313|Proteomes:UP000027222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL142419; KDR66929.1; -; Genomic_DNA.
DR STRING; 685588.A0A067SGU5; -.
DR HOGENOM; CLU_000443_1_0_1; -.
DR OrthoDB; 1386981at2759; -.
DR Proteomes; UP000027222; Unassembled WGS sequence.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 3.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR45628:SF7; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027222};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 311..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 702..719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 731..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 810..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 840..862
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 939..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1005..1031
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1257..1277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1298..1317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1337..1361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1382..1406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1511..1534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1591..1613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1625..1644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1656..1674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1709..1735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1806..1829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 533..769
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 810..1042
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1255..1540
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1591..1836
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2042..2073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2087..2123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2052..2066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2090..2115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2153 AA; 241543 MW; C7691BDEE02EFBC7 CRC64;
MENHDKYLHH TSPSRGTPNS ASSAVDFTGT PAGFSRPPSP ALEASDSTLA RRRSWGNRLR
NAGRADSESP DPIHPNHDAP PSPRRFAATN TTPVMAQDPF YVPNSERSRN HPYAIDSTRQ
YAPRMVSETY TDDSSTNSLA GPSTTSLIMQ RGHFEHEMED GHREDDEAHL TANMSHAGGG
SEEFSSGDPE NEGGSTPRSK RRTLRYSVTP SPLKKTETAY KSVKKNLRRM SLRVVNLANT
GLEGQLRLGD GDEKTKKSAG VDDDDDDDGP PEPDLKKVLP IRGRTLGFLG PDSKVRLALF
NFLVHPLTEP LILILIMLNA VVLTVQAFPN LTLPTANGPT LPPLVKGYFH SWEDYVLFVL
FIVFTLEAFA RICVTGFLFD PEVSIFTLFS SPASIQSEPY TPTPGPVPGM ARQTTLTRGH
SVTQRLRHFQ RKIMRPFALT QRPPVSSYPM TATGMPASIP TGQQYPTAQI YRDGGLPSRI
LDTARQLHST VRDPPEPTML SMAMRSDAHP DSIALPFRLS IGHLHDKTHR NVPYLRQSWS
RIDFIAIVSF WIMFALALSG NERGKYHIGV FRAMSVIRTA RLLTITSGTT TIMHSLKTAR
PLLTSVAYFV IFAMVLFSII GVQSFKGSLR RSCIITPTLG ETPHLRDGQF CGGYIDPDTL
RAVPYVQLNN LTAPAAKGYI CPLGQECREI SNPQSNIESF DAIYYAVLQV VIVATANGWA
PLMYSMIDSE FFISCFFFII AVIVLNFWLI NLFVAVITNT FSAIRSETQK SAFGAAPLVA
VDKGHDDGWA IVDGRKAATR SNPAKSIYAY TKWCWIILAL TSLALQATRT VDVSPTHELV
MFYGEIAITI AFDFEICLRI LATLPDWRSF FQHGNNWLDT ILAIGSTIIQ IPVIRRSALY
PWFTIFQLAR FYRVILVVPR MKPLLLAVFG NMYGLANMAL FLVIINFIAA LVAAQFLRGD
FGNNTTMNFG EIFNSFLAMY QVFSSENWTS VLYGAAIAEL PLGQTILALI FISAWMLFAN
FIVLQMFIAV INENFEVAEE QKKSKQASDY YSQRKARHGS VTWLRRLNPY RWVKANPETA
KVSNLPSNLI LPMQKTLVQD YSLSRADSRS LPVPVKKSVR KHRFMKPQHY SSKSLTALQQ
LFAGDVKTND ISLSTFRHNG QETSDNPSDP FDEEMERHLE LLASVNPDAG LAETANDEYH
ERIAQKADFI REHPSYDKVF WVIGQKNWLR KLFQKVVQPA RGDRIFGTPP SPIAHPIFQL
ILLLTIIGGI VVEAIATPAY RRHYFQQFGL TRGAWFEIAE AAFGFALFVE FMIKIIADGF
IFTPNGYLRS IWNCLDFIIM IGIIINVTTG LVFIGGLSRF TRSLKALRAL RLITLIDKMR
NTFQTLIISG ALRILDAAIL AILYMIPYAV WGLNIFNGRM NSCNDSNANG ISDCVGEYVN
TIYDNAFGFP VPRAWDNPSP STTFSFDSFR ASLLILFEIV SLEGWIDVMG VATSITGPGE
QPQTNASQGN AIFFVIYNLL GGVVILTLFV SIIIGNFRSK TGTALLTQAQ REWIDLQKLF
KRQKPSKLPK VRPTGVLRKW CFDRAVHKHG WWSRATTLLF VLHILALMTQ SFSTSNLADT
FRTDFFLGLM TIYLIDVFVR WYGLGWRSFR SNGWNLFDIV VATGSFITTL IVRFGDSGFV
TQQLQKLFLV SIAFKLVQRT NSLNMLFKTA VSSLPVILSL LGLWLILFIF FAILFMEVFG
LTKWGGAETR TTNYSSFGSA LVMLAFQSTG EGWNQYMHDY DLTYPRCTTS VFNDTDSDCG
STSWTFGLFI AWNLLSMYIF VNMFTGVVVE NFSYVFQASG SGSKSISREQ MRSFKKIWGE
FSNQKTGYLE RQRFGAFFYK LSGVFEVRIY PTEYSFRSIL SVCKDPLDKQ AWHSRAVDGL
DLGKLQTIVD QIDYVDVRKR KAVYSRLYHE ASISHEAGLG ISFTDMLTLL AHHKLILDAE
ALVLQDLVVR TETNKLVTDL VNLDRVRSLL KTISYRRRFL AHLEKKRAEK FDKEIPSIVV
ESMEGMPGTP PMSSRDISSA GYEHSSPGSP TPVDIRFSHS DYSLAMDAST GPRLQRSSRP
VSDYSTFSAD TSRSPRTSLF DDDPQDVVTA MQTSVWGDLM MEVAEEERGN KSF
//
