ID A0A067SWB6_GALM3 Unreviewed; 598 AA.
AC A0A067SWB6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN ORFNames=GALMADRAFT_250207 {ECO:0000313|EMBL:KDR74352.1};
OS Galerina marginata (strain CBS 339.88).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR74352.1, ECO:0000313|Proteomes:UP000027222};
RN [1] {ECO:0000313|Proteomes:UP000027222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KL142383; KDR74352.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067SWB6; -.
DR STRING; 685588.A0A067SWB6; -.
DR HOGENOM; CLU_001570_27_0_1; -.
DR OrthoDB; 4950799at2759; -.
DR Proteomes; UP000027222; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11063; CYP52; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR047146; Cyt_P450_E_CYP52_fungi.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24287; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR24287:SF1; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000027222};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 545..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 68475 MW; DBB42B4C4EE60671 CRC64;
MRDIPPGIQY LVKWSPRIVS PPIIAYIVGR ILSSAYDVRV SVWIMALWML ASLPLALTAA
VLWDELYVHL DAARMGAVMP PRVGDPYPGG FMGLINNIKA FKTGYPADGF QELSKRLGGY
TFNRRVLFEN RIITAEPEHI KAILATQFDD FEKGPETRFL FYPLLGTGVF AADGELWKFH
RSMTRPFFSK DRISHFDNFD RHAEAAITQL KHRQAEGFPV DFQDLVARFT LDSATEFLFG
NDVGSLSGEL PYPYYASSNP SNEKSSTDNH RASRFVSAFT EAQSVTAFRM RFGVHWPFAE
FWHDKLKKPM GVVHSFIDPI VAEAIKKKRE LADSGVVNKD RDDETLLENL VNSTEDPITL
RDEIMSLLVA GRDTTASTLT FTVYMLAEHP EFLRRLRQEI LEKVGPQRRP TYDDFRDMKY
LRAVINETLR LYPVVPFNVR TSKQATTWPN PKGKPFYIPA NTRTPYAVFM MHRRTDLWGP
DALEFDPDRF LDERLHKYLT PNPFIFLPFN AGPRICLGQQ FAYHEASFFL VRLLQTFSDI
SLVPDAQPPA SRPPAEWAED KKGRKGREKI RPRTHLTMYV QDGLWVSMKE ARLGEDGA
//
