ID A0A067SYA5_GALM3 Unreviewed; 1078 AA.
AC A0A067SYA5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Minichromosome loss protein Mcl1 middle region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GALMADRAFT_248867 {ECO:0000313|EMBL:KDR75022.1};
OS Galerina marginata (strain CBS 339.88).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR75022.1, ECO:0000313|Proteomes:UP000027222};
RN [1] {ECO:0000313|Proteomes:UP000027222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
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DR EMBL; KL142381; KDR75022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067SYA5; -.
DR STRING; 685588.A0A067SYA5; -.
DR HOGENOM; CLU_004219_1_0_1; -.
DR OrthoDB; 3686044at2759; -.
DR Proteomes; UP000027222; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR048591; Ctf4-like_C.
DR InterPro; IPR022100; Mcl1_mid.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19932; WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; 1.
DR PANTHER; PTHR19932:SF10; WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1; 1.
DR Pfam; PF20946; Ctf4_C; 1.
DR Pfam; PF12341; Mcl1_mid; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000027222};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 7..48
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 133..174
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 406..706
FT /note="Minichromosome loss protein Mcl1 middle region"
FT /evidence="ECO:0000259|Pfam:PF12341"
FT DOMAIN 714..808
FT /note="DNA polymerase alpha-binding protein Ctf4-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20946"
FT REGION 804..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..897
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..945
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 950..971
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1021..1058
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1078 AA; 119272 MW; 5BA480FF0706B578 CRC64;
MADKLAINTH GKGHTCMAFS KDGSRAFTGG KNAVIRIWTV SEGPEHEPAF VEDSGDAITS
LATADDGWIS GCLDGEARRY SRFNSEMDTV VTSFVSPIRC VAIDPTDRRI AVTSDEPKVK
VVELEDTERI VMLEGYASGV RSATWHPSST LLATCTSDGK IVIWNVAAEK PFIEKTLEGL
IPAVKDSESP EFSYDCSAVW HTSGQYFFVA TNGHEIVTIS RDDWTKTSTF SDKNVSGAVT
ALALSPNGVY LASASQSRVH IWSTQTRRVI TSQIGKPGSS ITQLAWSPNE NLLAWTDSDG
AFTRWRKPIS DNFPDPVKGS MATNGAATIP VKPKTGLDLF ADDTEQVTTG EKEDDDVDLD
DDIADIDDGW IVDDMDGALN APPAEEKGGR NGLVKEMVSI TQAQPPFQPG STPMENKKRY
LAYNMVGVIE VTDQDTHNIV NVEFFDRSLR KGYHFTDNFK HDLGYLGERG AVFACPPEND
HPAEVLFKPY SNWKANDWTY TLSKKGIKCL GIAAGALPLN SRNSADVELQ GYGNIVVATT
ENDLTFLSGT GRERRIMALG GDFVTMVASE EWVFVIHRAG STTIDGSQNL SYSIINFEDF
TVRQRDVLPV PKGHTLKWIG VTDQGAPAMF DTTGCVHILT KHRIPHHASW ARVMDTNTLE
RRQGKDESYW PVGITESNFM CLILKGRQEH PAFPRPLIQE LPMRIPFRQN SPQEETIERE
ALHVQIAFDS LDDELTTDDI ISREKAMDKE LIQLIQGACK AGNAPRAIEL TRLLHQIATL
DAAMKIADFY HLVGLKEKMG MVKADREENE DRLHSARNKR RRWLKQEPPL RQLAEAPAAS
SSRFDPLGDF RPPPVIERPG MARVTAPRIE TTRFTSHTPS SRTPERASWN DSAPRSPPST
DSKRKRDDLD ESFPTSDISM PPPKQKPNPF ARKANQDSNK NPFARKLDAS KTIQKSESFF
DKVDAAESET VPRKRPGAGN GKDAATLKGK DRKEGPKQAT LFGMLPKADK VSRPKKQPDT
APPTADTQET QIDSQMTDVT TVETETQEES QQRVGSPDWD ETQLVDAGDE SSMITSEL
//
