ID A0A067TEU5_GALM3 Unreviewed; 1621 AA.
AC A0A067TEU5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Raptor N-terminal CASPase-like domain-containing protein {ECO:0000259|SMART:SM01302};
GN ORFNames=GALMADRAFT_245577 {ECO:0000313|EMBL:KDR78409.1};
OS Galerina marginata (strain CBS 339.88).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR78409.1, ECO:0000313|Proteomes:UP000027222};
RN [1] {ECO:0000313|Proteomes:UP000027222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC {ECO:0000256|ARBA:ARBA00009257}.
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DR EMBL; KL142375; KDR78409.1; -; Genomic_DNA.
DR STRING; 685588.A0A067TEU5; -.
DR HOGENOM; CLU_001136_3_1_1; -.
DR OrthoDB; 103066at2759; -.
DR Proteomes; UP000027222; Unassembled WGS sequence.
DR GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR004083; Raptor.
DR InterPro; IPR029347; Raptor_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF14538; Raptor_N; 1.
DR Pfam; PF00400; WD40; 1.
DR PRINTS; PR01547; YEAST176DUF.
DR SMART; SM01302; Raptor_N; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000027222};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 125..278
FT /note="Raptor N-terminal CASPase-like"
FT /evidence="ECO:0000259|SMART:SM01302"
FT REPEAT 1476..1518
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..1018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1085..1141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1164..1197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1621 AA; 178351 MW; 75FAB543E0C3B857 CRC64;
MNATQTQPQV QPRPNGPKFA TGAGNWPRVK GAGGRTQSSD SDTEREYRST SRSDPSSQSQ
TRNSRGPNGQ RSPEGRVSAS IETSPDPSPP VPFWSAKRHL TCGNPTPGPP WSSKNIAWRG
SAPGKLKTAN AALVLCLNID VDPPDVIKTN PCAVLECWVD PHTMPSVKAL EAIGSNLQHQ
FEGLSLKITY KPILDPSLQD LRRFCTTLRK QAKDDAVLFY YNGHGVPKPT ASGELWCFNP
GYTQYIPVSL QEVQGWLGSP GVYIWDCSAA GHLLQNFNTY AERRDQEVNM LHGGYGDGAQ
PMMNSLQLAA CGANETLPSC PELPADVFTS CLTSPIDIAL RYFIMNHHLP NNITHDMVMQ
LPGDLKDRRT PLGELNWIFT AITDTIAWTT FSRETFTRLY RCDLLIASLF RNFLLAERIM
KNYHCTPHTY PPLPPTNTHP LWATWDLAVD TCLRQLPDLL SKSVNPASGL SSVTSNVGTT
PGRIGQTTRQ DPSLATGKTS DKPYQYVPSR FFADQLTAFE VWISRGGSAL TKRGPLSLPQ
QSSETNHTGQ PETNNSPSVD RDHSSSQQHL VPRKPPDQLP IVLQVLLSQP HRLRALILLS
QFVDLGPWAV HLVLTIGIFP YISKLLQAAG QDLRPVLIFI WARILAVDSS VQTDLYNTQG
YKYFSNILGL KNEDSLPNHS EHKAMCSFIL ASISRDFPHG QVACWNERVF DNCYDILENH
DFLLRQWTAL CIAQMWDAND EIKVYGVDRG TQDKLISMLS DDSAEVRAAA LYALGTFMGA
SGSADPSKQG GGGTGTMYQL EERVHFRMEV AVATGATLAI KDDASPMCRK ELLVVISCLV
KEWRGYFVVC AWLYWEEDRR WRSTGSMGHG PASHSHFQED DVTNQAVAEW LEGFGEDDML
REENRVLLSS FFTIFVLLLD LSVDPYEEVA TNAQTIVDYI MALLLESPFT RLESTSLHTP
PTVPADKRHS PQLGGRTRVA SLQSSPQFAH LPPPSPGGSS GIDRDHSRPP LSRNESTATT
LVGSTIKRTS SFANALKVLT GGIAFPTTNN EDGRASPSLA SALMPSQLRS SSERHGLAQA
HVHEAAANDV SRPPSPNMNL AKYTSPYSYP PSIGDNTSDR GMSPPPTQSY FDGQQSQSQP
SIDFLPCDVM EALMEEDMER LRARRKAGLH GRRSHSHGHG GGGGLPSPSN STFSMDSNSS
SVILGLGTGA GIRDMLPLKS TFYDWCAEYF KEPQMRQTEA DEPGSVQYNY QVWRQLRNDQ
VIKETDAQAP LAENGHWDRP VATLTIPGGH PLTMAFHSYD KQIIVANEND MISVWDWNTR
KRLNYFCNGN PKGTSITALE IINQDIGGII LTGSADGIVR LYRNYDPSLE QGPLQMVSAF
RGLNEIISSR QGTGLVMDWK QSGGILLIGG DSRVIKVWDA GTETQGLDLE TNSESPVTAI
ASDSGSTKTF LASFADGVVK LFDRRLEDED AIVRTYADHT TWVQNVRWHP TLSGQFLSAG
IDGQVKLFDL RGSDYATKTW NAHPNGLSAF DVHPIANVFA ANSSISPVYW RAQRIVVQSV
NKPTPLSAFN VPTGLTTPPI RGLPSLFIPR SSSLVFHPMQ MLYATGGPDG CVRIMGCGLP
Q
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