ID A0A067TKL0_GALM3 Unreviewed; 291 AA.
AC A0A067TKL0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=GALMADRAFT_137297 {ECO:0000313|EMBL:KDR79473.1};
OS Galerina marginata (strain CBS 339.88).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR79473.1, ECO:0000313|Proteomes:UP000027222};
RN [1] {ECO:0000313|Proteomes:UP000027222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
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DR EMBL; KL142373; KDR79473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067TKL0; -.
DR STRING; 685588.A0A067TKL0; -.
DR HOGENOM; CLU_007383_6_8_1; -.
DR OrthoDB; 1133at2759; -.
DR Proteomes; UP000027222; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000027222}.
FT DOMAIN 73..236
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 291 AA; 32513 MW; 7450891E30E6F73A CRC64;
MAVKPTNERY LVIGGSGFLG SYIVQAPVDR REPSEADVVA GVKYFCGDIL NKKELLDCLE
ESAASTVFHT APSVKSFVFT SSTSVVWADQ DVSGLNEDEV TIPEKKYEAY NHTKGIAEAM
VLQADGVEDM KVAAFRPPRY RQAMWRLADA YNNGQHKYQI GKNTNFVDLC YVGNVADAHV
LAADRLSVAA SSPSSPDEVF GQAFFITEGK PGLYWEFPRM VFRQLGDDGK GIVELPRRLC
LVLAFFSELW TSIFRGVPRF PRFIAVIATQ EQWYNIDKVF LIFMQLVASP H
//
