ID A0A067TVX0_GALM3 Unreviewed; 624 AA.
AC A0A067TVX0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 13-SEP-2023, entry version 35.
DE RecName: Full=Actinin-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GALMADRAFT_56855 {ECO:0000313|EMBL:KDR83148.1};
OS Galerina marginata (strain CBS 339.88).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Galerina.
OX NCBI_TaxID=685588 {ECO:0000313|EMBL:KDR83148.1, ECO:0000313|Proteomes:UP000027222};
RN [1] {ECO:0000313|Proteomes:UP000027222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 339.88 {ECO:0000313|Proteomes:UP000027222};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
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DR EMBL; KL142369; KDR83148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067TVX0; -.
DR STRING; 685588.A0A067TVX0; -.
DR HOGENOM; CLU_005217_0_2_1; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000027222; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000027222};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 12..118
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 127..233
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 487..522
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 624 AA; 71202 MW; 79B2F2720410A193 CRC64;
MVVDTPETRS RDTQERTFCK WLNTKLEAHG YPTMSSLVKD LSDGVRLIQL MEIMGDTSLG
RYNKTPRMRV QKAENVNKAL EFITSRGVKL TNIGPEDIID GNLKLILGMI WTLILRFTIA
DISEEGLSAK EGLLLWCQRK TEPYKEVNVQ DFSYSWSDGL ALCALIHCHR PDLLDFNALD
KTDRHGNTRL AFKVAAEHLN IPQLLEVEDL CDSAHPDERS VMTYIASFFH AFSTMDQAET
VSRRVEKFAE LMQSVWLIRN DYERRVKLLL SALSSIQAQW SSQLLDGSYA DAKEQSAAFT
IYKQTTKRSW VTERQDLATL FGNVQTKLKT YALREYVPPV GLSLADLDVA WQRLLEAEAE
RSRRINAQIR LIKETLRKKF AKLANDFEQK LHEISSELTA IEGPLEGQQK QVQQIQTRIP
ALSETLATVA QAETECEAAN VEENDYTIFT CQDLEFELEL VMHSIMKKIT FIDNQIVSRN
MTNLTPAQLE EFESTFRYFD KDETNTLSQA EMIAALASLG IVYSEEDMDL IYDQLVADYG
AVTFEAFINL LVEITEDQTS PDQLRDSFRG IAKDKPFVTE LDLRIAHLPA ASIDYLREAM
PRGQSNGGEA EYDYERFIDE VFST
//
