ID A0A068QNP4_9GAMM Unreviewed; 565 AA.
AC A0A068QNP4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=yehU {ECO:0000313|EMBL:CDG16191.1};
GN ORFNames=XDD1_0488 {ECO:0000313|EMBL:CDG16191.1};
OS Xenorhabdus doucetiae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351671 {ECO:0000313|EMBL:CDG16191.1, ECO:0000313|Proteomes:UP000032721};
RN [1] {ECO:0000313|EMBL:CDG16191.1, ECO:0000313|Proteomes:UP000032721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FRM16 / DSM 17909 {ECO:0000313|Proteomes:UP000032721};
RA Genoscope - CEA;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FO704550; CDG16191.1; -; Genomic_DNA.
DR RefSeq; WP_045968336.1; NZ_VNHN01000005.1.
DR AlphaFoldDB; A0A068QNP4; -.
DR STRING; 351671.XDD1_0488; -.
DR KEGG; xdo:XDD1_0488; -.
DR HOGENOM; CLU_020473_3_3_6; -.
DR OrthoDB; 2514702at2; -.
DR Proteomes; UP000032721; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR PANTHER; PTHR34220:SF10; SENSOR HISTIDINE KINASE BTSS; 1.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00065; GAF; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:CDG16191.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:CDG16191.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..365
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
SQ SEQUENCE 565 AA; 62476 MW; 7955D6BAFA7FD6DB CRC64;
MYEFNLVLLL LQQMCVYLVI AWLLSKTPLF IPLLQVTVRL PHKLMCYVIF SIFCIMGTYF
GLNVNDSIAN TRAIGAVLGG FLGGPTVGAM VGFTGGLHRY SLGGMTAFSC MVSTIVEGVL
GGLVHIYLMK KGQLNKLLNP WTAAVVTFFA ECTQMGIILL LANPFGEALS LVKDIAAPMI
IANSIGAAMF IRILLDRRAI FKKYTSAFSA QALKIAVCTE GILRKGFNED NSMRVAKVIY
QELEIGAVAI TDREKLLAFI GIGSDHHLPG TPIAAKQSRR AIENNEVVYA DGNETPYCCS
LSPTCKLGSA LVIPLRGENQ QVIGTIKLYE AKNRLFSSIN RTLGEGIASL LSAQILAGQY
ERNKQSLLQS EIKLLHAQVN PHFLFNALNT LQAVIRRDSQ QAGQLVQYLS TFFRKNLKRP
EDIATLDNEI EHVNAYLQIE KARFREHLQI AIEIPESLRN ARLPAFSLQP MVENAIKHGT
SQLLETGRIT IRAHQEANLL LVEIEDNAGL YCPQKMGDGL GMSLVDKRLR LRYGTQYGVR
VDCQPEAFTR VILCLPLEKE TKKAA
//
