ID A0A068R476_9GAMM Unreviewed; 440 AA.
AC A0A068R476;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000256|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000256|HAMAP-Rule:MF_00671,
GN ECO:0000313|EMBL:CDG22003.1};
GN ORFNames=XPG1_2348 {ECO:0000313|EMBL:CDG22003.1};
OS Xenorhabdus poinarii G6.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1354304 {ECO:0000313|EMBL:CDG22003.1, ECO:0000313|Proteomes:UP000032735};
RN [1] {ECO:0000313|EMBL:CDG22003.1, ECO:0000313|Proteomes:UP000032735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G6 {ECO:0000313|EMBL:CDG22003.1,
RC ECO:0000313|Proteomes:UP000032735};
RA Genoscope - CEA;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. TolB occupies a key intermediary
CC position in the Tol-Pal system because it communicates directly with
CC both membrane-embedded components, Pal in the outer membrane and TolA
CC in the inner membrane. {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000256|ARBA:ARBA00009820,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
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DR EMBL; FO704551; CDG22003.1; -; Genomic_DNA.
DR RefSeq; WP_045959042.1; NZ_FO704551.1.
DR AlphaFoldDB; A0A068R476; -.
DR STRING; 1354304.XPG1_2348; -.
DR KEGG; xpo:XPG1_2348; -.
DR HOGENOM; CLU_047123_0_0_6; -.
DR OrthoDB; 9802240at2; -.
DR Proteomes; UP000032735; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR NCBIfam; TIGR02800; propeller_TolB; 1.
DR PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF04052; TolB_N; 1.
DR SUPFAM; SSF52964; TolB, N-terminal domain; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00671};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00671};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_00671};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_00671}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT CHAIN 30..440
FT /note="Tol-Pal system protein TolB"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00671"
FT /id="PRO_5008980859"
FT DOMAIN 31..130
FT /note="TolB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04052"
SQ SEQUENCE 440 AA; 47746 MW; 1E6A6F7E1A421B2B CRC64;
MKQVFAQIFK QKFRIILGFL MMWAALAHAE VRIEITQGVD SARPIGIVPF KWSGAGEAPE
NISSIIAADL RNSGKFNPID PNRMPQQPTA ASEVTSGAWS ALGIDSVVIG HIQPSADGKF
LVSYQLVDVA GAPGTVLEQN QFTIEQKWLR FAAHTISDQV FEKLTGIKGA FCTRIAYVVV
KNNQESKSPY ELYVSDYDGY NQTRVHSSPE PLMSPAWSPD ASKLAYVTFE GGRSSLIIQT
LTTGEVRHVA SFPRHNGAPA FSPDGTKLAF ALSKTGSLNL YVMDLASGQI HQVTDGRSNN
TEPSWMPDSQ TLVYTSDQGG RPQLYKIDIN GGAPQRLTWE GSQNQDADVS PDGSFIVMVS
SANGKQHIAK QDLATGSVQI LTDTFLDETP SIAPNGTMVI YSSTQGWGTV LQLVSTDGRF
KARLPATNGQ VKSPAWSPYL
//
