ID   A0A068RJS2_9FUNG        Unreviewed;       578 AA.
AC   A0A068RJS2;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   03-MAY-2023, entry version 31.
DE   SubName: Full=Transcription factor {ECO:0000313|EMBL:CDH49955.1};
GN   ORFNames=LCOR_01680.1 {ECO:0000313|EMBL:CDH49955.1};
OS   Lichtheimia corymbifera JMRC:FSU:9682.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Lichtheimiaceae; Lichtheimia.
OX   NCBI_TaxID=1263082 {ECO:0000313|EMBL:CDH49955.1, ECO:0000313|Proteomes:UP000027586};
RN   [1] {ECO:0000313|EMBL:CDH49955.1, ECO:0000313|Proteomes:UP000027586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JMRC:FSU:9682 {ECO:0000313|Proteomes:UP000027586};
RA   Schwartze V.U., Winter S., Shelest E., Marcet-Houben M., Horn F.,
RA   Wehner S., Hoffmann K., Riege K., Sammeth M., Nowrousian M., Valiante V.,
RA   Linde J., Jacobsen I.D., Marz M., Brakhage A.A., Gabaldon T., Bocker S.,
RA   Voigt K.;
RT   "Gene expansion shapes genome architecture in the human pathogen
RT   Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient
RT   terrestrial Mucorales (Mucoromycotina).";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Su(H) family.
CC       {ECO:0000256|ARBA:ARBA00009704}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDH49955.1}.
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DR   EMBL; CBTN010000005; CDH49955.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A068RJS2; -.
DR   STRING; 1263082.A0A068RJS2; -.
DR   VEuPathDB; FungiDB:LCOR_01680.1; -.
DR   OrthoDB; 1384914at2759; -.
DR   Proteomes; UP000027586; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 2.80.10.50; -; 1.
DR   Gene3D; 2.60.40.1450; LAG1, DNA binding domain; 1.
DR   InterPro; IPR015350; Beta-trefoil_DNA-bd_dom.
DR   InterPro; IPR036358; BTD_sf.
DR   InterPro; IPR040159; CLS_fam.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR015351; RBP-J/Cbf11/Cbf12_DNA-bd.
DR   InterPro; IPR037095; RBP-J/Cbf11_DNA-bd_sf.
DR   PANTHER; PTHR10665; RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS; 1.
DR   PANTHER; PTHR10665:SF0; SUPPRESSOR OF HAIRLESS PROTEIN; 1.
DR   Pfam; PF09270; BTD; 1.
DR   Pfam; PF09271; LAG1-DNAbind; 2.
DR   SMART; SM01268; BTD; 1.
DR   SMART; SM01267; LAG1_DNAbind; 1.
DR   SUPFAM; SSF110217; DNA-binding protein LAG-1 (CSL); 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027586};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          120..241
FT                   /note="RBP-J/Cbf11/Cbf12 DNA binding"
FT                   /evidence="ECO:0000259|SMART:SM01267"
FT   DOMAIN          242..412
FT                   /note="Beta-trefoil DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM01268"
FT   REGION          37..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   578 AA;  63945 MW;  C7B4096F215715BC CRC64;
     MNQTSPILSE QIYGSSKKLQ LIKDTMSIQS LLVTNGDHDN NAKKTTNTTT TTTTLIASPK
     RRWPVNNNTT TNDEDNNKNN DNNELTANDI ERAPKMRKTT SVQPGQRGPP PIPYGQPMTT
     LTCLHAAVAQ KSYGSEKRFL CPPPVVSVAH PRLPESHISM AIISENGERP LEQRTLLDEH
     LSGSFKYLHV TGTAKAKQFS LRVSLSSSHH HQPQPYATFV SNPISIISKP SKKTAKARNV
     STCILANAPV SLFNRINSQT VRTKYLTSDG KRLCAKNATW SAFDIILVRP PYAPCPMPVT
     YGAEIILRDT STGIQSPPVI LRKVDKGRIT QAFGPVSQMQ KVALQLASSV GQQQPLYLCA
     NSAQESETVS TSPTTSSSSS PLSWIEFLPS RIVQPDNKVE LAYEEVDDSL FWTIVGIHKF
     EYSFYDPLST SLSSISPFPV VSSAQYNPTS HTLDLFGQHL VHHQASLLDC WLGPHGPLPA
     KLVNSQAEQP GSARQSTHIT IDLPTTQDLL QYHYKDQVPR QQHLAMMTRA EDGVQHLELP
     LLLVRQDTHV VYHSGKALTL HSDPRRCSVM ITNWSVSK
//