ID A0A068RZH5_9FUNG Unreviewed; 1014 AA.
AC A0A068RZH5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Muts protein homolog 4 {ECO:0000313|EMBL:CDH55140.1};
GN ORFNames=LCOR_06315.1 {ECO:0000313|EMBL:CDH55140.1};
OS Lichtheimia corymbifera JMRC:FSU:9682.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Lichtheimiaceae; Lichtheimia.
OX NCBI_TaxID=1263082 {ECO:0000313|EMBL:CDH55140.1, ECO:0000313|Proteomes:UP000027586};
RN [1] {ECO:0000313|EMBL:CDH55140.1, ECO:0000313|Proteomes:UP000027586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMRC:FSU:9682 {ECO:0000313|Proteomes:UP000027586};
RA Schwartze V.U., Winter S., Shelest E., Marcet-Houben M., Horn F.,
RA Wehner S., Hoffmann K., Riege K., Sammeth M., Nowrousian M., Valiante V.,
RA Linde J., Jacobsen I.D., Marz M., Brakhage A.A., Gabaldon T., Bocker S.,
RA Voigt K.;
RT "Gene expansion shapes genome architecture in the human pathogen
RT Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient
RT terrestrial Mucorales (Mucoromycotina).";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDH55140.1}.
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DR EMBL; CBTN010000027; CDH55140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068RZH5; -.
DR STRING; 1263082.A0A068RZH5; -.
DR VEuPathDB; FungiDB:LCOR_06315.1; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000027586; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000027586}.
FT DOMAIN 383..711
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 727..922
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 931..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 940..963
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 111897 MW; 171237143D65EBC2 CRC64;
MRPKHRLLSS TSSSSSSTAE ASSNPNTSSR SNGRVKKNKA IDMTRVDHPP SVLSTKSSAL
DTLRYAYNNK FAGSSSLLPS SNSSTTTSNH GDNKALPFRR RKIASTEGSF IMDRKSSIAS
TTPSLSQKRL PTSTPINARE RSLPSTSSSR LHSHGSLPPK AALTPPPTQS LAYSGRHSTV
TSSPSHGFQP ASASRPATIN RPLVPATVAS VRDRRLMVLA EGRGVSPEVG ICIVHVTTGE
CTLSQVPDTP SYSRTLHKIH LNDPHNILFA NTALEPGTTQ LYQLVNENFP EISTSVIPRK
YFSDDVGMKD LQEYGLEEDA SSLMLGLSTK YYCLAAVAAA FKYIAENEGL RFARHTVKFT
YQGVEDVATA RNLELVSNIM RRNSKDTLYG VLNHTVTPMG SRLLRTNILQ PSTDEALIRR
RLDAVQELIS QENLLFDIQA ALKPVADLDH IIADIVRIPT TQDLHYTESK INNVIRLKIL
LAAVKTVANS LEACNLNDLL GAILELLSDP KLDEFVQDIN QVLHDDVGVQ KTALGLRHQR
CYAVKAGVNG LLDVARQSYK ETMEDIYEMA TEYCQTTNLN IKLQFNASRG FFLTLPVDQL
KGGEGDLPSI FINVIKKKKL YSFATIELLQ KNSRMNESLA EIYLMSDNTV TELLQRFHAD
IGVLYKVTEA IAMLDMLLSF AHSCSLSQHV RPEFTSTLAI EAGRHPIMEH IQKEPVVPND
TFASLSSSFQ IITGPNMSGK STYIRQVALL TIIAHMGSFV PASYASFRLC DQILSRLLGN
DGCLEQNTSS FILEMREAAY IIQNITDTSL VVLDELGKGT APYDALGITA AIAECLSSSK
AYCFFATHFH QLTHVLHIYP NIVNLQLHVD VTNNPESRDC TLSYSYTVRD GAVAKDQHYG
LKTAELLGFP SQIILRALQI TEKLAQPLHA EPYKDSQPQS MMAVDGNSSK SPDNNQNNPS
PEGDDAEDQA RCRTLYWFAD KMLQLQGAPD EVFYDQIIHV KEMLAKQIEP LESE
//
