ID A0A068TPF3_COFCA Unreviewed; 570 AA.
AC A0A068TPF3;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=beta-ketoacyl-[acyl-carrier-protein] synthase I {ECO:0000256|ARBA:ARBA00013191};
DE EC=2.3.1.41 {ECO:0000256|ARBA:ARBA00013191};
GN ORFNames=GSCOC_T00021731001 {ECO:0000313|EMBL:CDO97819.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDO97819.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; HG739086; CDO97819.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068TPF3; -.
DR STRING; 49390.A0A068TPF3; -.
DR EnsemblPlants; CDO97819; CDO97819; GSCOC_T00021731001.
DR Gramene; CDO97819; CDO97819; GSCOC_T00021731001.
DR InParanoid; A0A068TPF3; -.
DR OMA; EPCEEYY; -.
DR PhylomeDB; A0A068TPF3; -.
DR Proteomes; UP000295252; Chromosome 4.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR03150; fabF; 1.
DR PANTHER; PTHR11712:SF332; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE II, CHLOROPLASTIC; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..570
FT /note="beta-ketoacyl-[acyl-carrier-protein] synthase I"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001656945"
FT DOMAIN 153..563
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 570 AA; 61225 MW; 7EE8CF1D1E4E4607 CRC64;
MMASSVASPL CTWLVAACMS ASCEKDHFLK LPSIFRCSRR LSRSARRRKV VVPQFLNAGG
AGLVSSFCAS GIQNWLNSCL TFEPCEEYYN SEGLASSLSC FSENAFSLFG HKAEPVTRRQ
RRMNRAAISG KAMAVAVKPQ KDTIAKKKSL TEKRRIVVTG VGVVSSLGHD ADIFYSNLLE
GVSGISQIET FDCSEFPTRI AGEIKDFSAD GWVAPKLCKR ADKFMLYMLT AGKKALADGG
ITEDVMEEID KAKCGVLIGS ALGGMKVFND AIEALRVSYK KMNPFCVPFA TTNMGSAMLA
MDLGWMGPNY SISTACATSN FCMLNAANHI IRGEADIMLC GGSDSAIIPI GLGGFVACRA
LSQKNGDPTR ASRPWDVDRD GFVMGEGAGV LLLEELEHAK RRDAKIYAEF LGGSFTCDAY
HMIEPHPEGA GIVLCIEKAL AQSGVAREDI NYINAHATST PAGDLKEFEA IMRCIGQNPE
LKMNSTKSMV GHLLGAAGAV EAVATVKAIQ TGWIHPNINL ENPDKGVDTS VLVGPKKEQL
EIKVALSNSF GFGGHNSSIL FAPYKPDEGD
//
