ID A0A068TXG5_COFCA Unreviewed; 1167 AA.
AC A0A068TXG5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=GSCOC_T00032751001 {ECO:0000313|EMBL:CDP00702.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP00702.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
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DR EMBL; HG739089; CDP00702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068TXG5; -.
DR STRING; 49390.A0A068TXG5; -.
DR EnsemblPlants; CDP00702; CDP00702; GSCOC_T00032751001.
DR Gramene; CDP00702; CDP00702; GSCOC_T00032751001.
DR InParanoid; A0A068TXG5; -.
DR OMA; KMWKMSK; -.
DR PhylomeDB; A0A068TXG5; -.
DR Proteomes; UP000295252; Chromosome 11.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF146; DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH5, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 282..449
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 536..710
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1078..1143
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 21..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1167 AA; 131782 MW; A3D0D6B68A261E2E CRC64;
MKDRLQSSYG AVYVPPHHRL RSVISKTSTP TAPPASPPRA IHSKPALTNS DDKHSSFVNS
RNNTYLPPHH FHQQLKKKSS TDDVSSEGSD RDIDLPVHPG GSSFDNIDSW KWKLTTLLRN
KDNQEVVSRE KKDRRDYEDI AALASQMGLY SHLYAKVVVV SKAPLPNYRF DLDDKRPQRE
VILHPGILRR VDYYLREYMS QKPKGMDTFS RSSSNGSIAT DEGLFEQPEP FSHNKAAMKK
IISRRSLQMH TERQTWQESQ QGQKIMEFRR SLPAYKEKDA ILSAIANNQV VIISGETGCG
KTTQIPQYIL ESEIEATRGA MCNIICTQPR RISAMSVSER VAAERGELLG ETVGYKVRLE
GVKGRDTHLL FCTTGILLRR LLVDRNLKGV SHVIVDEVHE RGMNEDFLLI VLKDLLPHRP
ELRLILMSAT LDAELFSSYF GRAPMVHIPG FTYPVRTHFL ENILEMTGYR LTPYNQIDDY
GLEKLWKMNK QAPRKRKSQI ASAVEDALRA ADFEDYSPLT RESLSCWNPD CIGFNLIEHL
LDYICQNEKP GAVLVFMTGW DDISALKEKL QGHQIIGDPN QVLLLTCHGS MASSEQSLIF
NKAEDGVRKI ILATNIAETS ITIDDVVFVI DCGKAKETSY DALNNTPCLL PSWISKVSAK
QRRGRAGRVQ PGECYRLYPR CVYDAFADYQ LPEILRTPLQ SLCLQIKSLK LGSISEFLSR
ALQSPELLAV QNAIEYLKVI GALDENENLT VLGRYLTMLP MEPKFGKMLV LGAIFYCLDP
ILTIVAGLSV RDPFLSPLDK KDLAEAAKAQ FSQDYSDHLA LVRAYEGWKD SEMDLAGYEY
CWKNFLSAQS MKAIDSLRKE FYLLLKDTGL VDSNSTTYNT WSYDEHLLRA VICYGLYPGI
CSVVPNEKSF SFKTMEDGQV LLYSNSVNGR ESRIPYPWLV FNEKIKVNSI FLRDSTAVSD
SVLLLFGGSV LKGDMDGHIK MLGGYLEFFM SPSVAEMYQS LRRELEELIQ TKLLNPRMDI
HSHHALLSAI RLLITEDQGD GRFVFNRQVL QPPKPSAVAV AAPPTLMSRT ESGPGGDNSK
SQLQTLLTRA GYAAPIYKTK QEKNNQFLAT VEFNGVQIMG HPCNNKKQAE KDAAAEALEW
LLEGHQRGHD YIEQMSLFLK KSKKEHR
//
