ID A0A068U622_COFCA Unreviewed; 470 AA.
AC A0A068U622;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Transcription factor {ECO:0000256|RuleBase:RU369104};
DE Short=bHLH transcription factor {ECO:0000256|RuleBase:RU369104};
DE AltName: Full=Basic helix-loop-helix protein {ECO:0000256|RuleBase:RU369104};
GN ORFNames=GSCOC_T00016185001 {ECO:0000313|EMBL:CDP03717.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP03717.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369104}.
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DR EMBL; HG739095; CDP03717.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068U622; -.
DR STRING; 49390.A0A068U622; -.
DR EnsemblPlants; CDP03717; CDP03717; GSCOC_T00016185001.
DR Gramene; CDP03717; CDP03717; GSCOC_T00016185001.
DR InParanoid; A0A068U622; -.
DR OMA; QVYGYEQ; -.
DR PhylomeDB; A0A068U622; -.
DR Proteomes; UP000295252; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:EnsemblPlants.
DR CDD; cd11449; bHLH_AtAIB_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR045084; AIB/MYC-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR025610; MYC/MYB_N.
DR PANTHER; PTHR11514; MYC; 1.
DR PANTHER; PTHR11514:SF53; TRANSCRIPTION FACTOR BHLH3; 1.
DR Pfam; PF14215; bHLH-MYC_N; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369104};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU369104};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU369104}.
FT DOMAIN 320..369
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 283..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 470 AA; 52094 MW; B650A3608E2D9612 CRC64;
MGEKFWLIEE DKALVESVLG AEAVQFFVWL ASSNILSEFA APAGVAGVQD GLSKVVEGSD
WTYAIYWQVS TSKSGKSALI WGDGHCRDPR GTEKMDGNDY RDQRFAGGDR RKQALQKIHA
CFGGAEDDNV AAKLDSVSEL EMFYLTSMYY AFPFDKPSTP SQAFNTSRTI WVSDPRSCSE
NYQSRASLAK SARIETVVFV PFKSGVVEIG SGKSLSEDPN VVQMVKTSIT PNVVHPKTAP
KIFGQELSLG GGKSGPISIS FSPKVEDDSL FVSDSYELQA LAGYGPSNGY RSDDGEDDSL
MLSDDRRPRK RGRKPANGRE EPLNHVEAER QRREKLNQRF YALRAVVPNI SKMDKASLLG
DAIAYITDLQ KKIRIMEAER EMVNDRQKQP AVTDIDLQER HEDAVVQVSC PLDVHPVSRV
IKAMREHQIV AQESDVSLTE NGEVVHTFSI RTQGGDAEHL KEKLTTALFN
//
