ID A0A068UI80_COFCA Unreviewed; 644 AA.
AC A0A068UI80;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Mechanosensitive ion channel MscS domain-containing protein {ECO:0000259|Pfam:PF00924};
GN ORFNames=GSCOC_T00024566001 {ECO:0000313|EMBL:CDP07333.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP07333.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HG739110; CDP07333.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068UI80; -.
DR STRING; 49390.A0A068UI80; -.
DR EnsemblPlants; CDP07333; CDP07333; GSCOC_T00024566001.
DR Gramene; CDP07333; CDP07333; GSCOC_T00024566001.
DR InParanoid; A0A068UI80; -.
DR OMA; GMINIFR; -.
DR PhylomeDB; A0A068UI80; -.
DR Proteomes; UP000295252; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR016688; MscS-like_plants/fungi.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
DR PANTHER; PTHR31618:SF1; MECHANOSENSITIVE ION CHANNEL PROTEIN 6; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR PIRSF; PIRSF017209; Memb_At2g17000_prd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 457..515
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 226..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 74103 MW; 9C34837E739DCE44 CRC64;
MESSFSRVTV PRKAKLFAKS LKSRLDAPRC GNSQEDEDWF LDEDVLAGTR PKKMSLSTLF
QLVSLVLVMI ILVCTLSLTK LKKTKLWDLP LWKWEMLISV IISGHLVTGW GVRIIVFTTE
QAFVSKNMRV LYFVYGMKKA VQHCIWLTLI LIVWHYLVAE NMGLETRSKA LTRVSKALLC
LVVGSLVWLV KVFFVKVLAS SFYNKTFFER AKVYLFKQYV IKKLSAPPDG GEQSEEDAAK
VGGETKPKDL PQFLRRGFSK RKGQESSKGR QRKLVRRKAP GLLLKMWLSM VHSGLLDGLS
TLDEGLPDSS DDEDEKSLSC KAEKVAKKIF KNVAKNSEVI VLEDLKQFMK ADKASLAMHL
FEGTAGTEGI NEHSFTRWMV DAYKERIYLQ LSLSDTKTAV DELHHLMDAV VIIIIVIIWL
LIFELAVAHF IVIISSQLLL VGFIFQNTLK TVFEAIIFLF IMHPYDVGDR CEIEEVQMVV
VEMNILTTEF ERYDGQKIIY PNSILATKPI GNYNRSPHMG DQIEFSIHIS TPWDKILTLQ
HNIRSYVESN AKHWYPDPTI LIKDVEDMNR LVMVVWPKHR MNHQDMRQRW LRRALLVDEM
IKIFRELDIQ YRTLPLDMNV RNMPAATSNK FPSNWTTCSG SERP
//
