ID   A0A068UTI5_COFCA        Unreviewed;       959 AA.
AC   A0A068UTI5;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GSCOC_T00035123001 {ECO:0000313|EMBL:CDP11855.1};
OS   Coffea canephora (Robusta coffee).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC   Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX   NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP11855.1, ECO:0000313|Proteomes:UP000295252};
RN   [1] {ECO:0000313|Proteomes:UP000295252}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX   PubMed=25190796; DOI=10.1126/science.1255274;
RA   Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA   Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA   Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA   Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA   Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA   Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA   Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA   Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA   Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA   Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA   Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA   Lashermes P.;
RT   "The coffee genome provides insight into the convergent evolution of
RT   caffeine biosynthesis.";
RL   Science 345:1181-1184(2014).
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   EMBL; HG739144; CDP11855.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A068UTI5; -.
DR   STRING; 49390.A0A068UTI5; -.
DR   EnsemblPlants; CDP11855; CDP11855; GSCOC_T00035123001.
DR   Gramene; CDP11855; CDP11855; GSCOC_T00035123001.
DR   InParanoid; A0A068UTI5; -.
DR   OMA; HETFHEK; -.
DR   PhylomeDB; A0A068UTI5; -.
DR   Proteomes; UP000295252; Chromosome 5.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155:SF759; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000295252}.
FT   DOMAIN          101..186
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          256..502
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   959 AA;  108836 MW;  DB28FBD4DB04CF93 CRC64;
     MSAIYDNWER LVRATLRRED LLLSALRTPS DISTVSESSS FNFSDPSHSA SSFNISSLLV
     GDSFTYHQNL QATDYISGTN LIKHRGSNVG LMGALGNAVA QELVKDLALA TQHESRYALQ
     FPTRFRILEE ELKIMQVFIS EASKLKENRE TVRTVLPVLR ELTYEADDLV LDCKIRDDYQ
     KMKGTSGFSL YPSEIYFRYE TGKKLTEINS QIKRMREYLK PYYTLGQRTN SENGNDTKRR
     STVPVIDQSE VVGLKEDVAK VRGWILGQNE PLLHLAIVGL GGLGKTTLAK MIYRDVNLTR
     RFQEKIWVSV SQPVNEDEIM KSILKQLNAD GSRSPKGYML STIHGLLSEK TYLIVLDDVW
     STDDGWWERI SGGLPMKEGH NSCIIITSRI KTVVKNMGVQ DAQIHQPRFL NDEESWKLFC
     KVARLSEVGE RNTKLVEEGK EIVKKCGGFP LAIKTVGGLL SSEERSSRRI HETFHEKLTN
     IGDNFSKGNP HVIASLQLSY DELPAFLKPC ILCFSIYPED YEVDADQLIR WWVGEGFVSG
     NNTETATESA LKCLSELISR CLVEVAQQRN YDGSVYTCKV HNVVRDLTIK IAREEDFCSF
     DANGNHIADV GCRRLGVTEE TKLQTLHGNS KLRALLLTKT DYIGFNRNIE LAKVKSLRVL
     DLSRVKLDRI RVEDLWRWIT SQKRLAYLSL RHVAKLLEIP NSIGKLWGLQ VLILGECKDL
     KKLPTSIINL PRLIILDVGN CPSLRCLPQG FSRLSNLQEL YGFKIAGTGN AAGSHLSELY
     ALTELRVLHI DLTEDSTIED QELDALELLE KLKLLSINAG DCKDEDILSK LNKLSPPSSI
     EELYLKHYLG ETTPAWINPR SLQQLQYLSV ENSGIEKMNQ EFWGDEEYKW DVKGLCLKFC
     QRLEVSWEEL QAVMPQIRHL EVSQCNLLAS FPCDVEAVGF WHKDTKEKNV SENVFSQED
//