ID A0A068V5Q2_COFCA Unreviewed; 1155 AA.
AC A0A068V5Q2;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDP15849.1};
GN ORFNames=GSCOC_T00016736001 {ECO:0000313|EMBL:CDP15849.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP15849.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC races carrying the avirulence gene Avr1. Resistance proteins guard the
CC plant against pathogens that contain an appropriate avirulence protein
CC via an indirect interaction with this avirulence protein. That triggers
CC a defense system including the hypersensitive response, which restricts
CC the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; HG739195; CDP15849.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068V5Q2; -.
DR EnsemblPlants; CDP15849; CDP15849; GSCOC_T00016736001.
DR Gramene; CDP15849; CDP15849; GSCOC_T00016736001.
DR InParanoid; A0A068V5Q2; -.
DR PhylomeDB; A0A068V5Q2; -.
DR Proteomes; UP000295252; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR021929; R1A-like_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF12061; NB-LRR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252}.
FT DOMAIN 141..365
FT /note="Late blight resistance protein R1A-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12061"
FT DOMAIN 440..668
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 316..350
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1155 AA; 131323 MW; 719E662011A37B33 CRC64;
MASTRVDSVL HNLELLHNNL EKRDSFETGF SNLREDFEAL KLNLLFLKPV LLCARNWSSD
QLKVRLRAFL SKIEAPVNRS GMDIKSLNLR SKSSFNLKSV VTALKPVVSN LLGNIKSFKQ
DIIDIYETLS SCSSSESGSC LRDYELVDFI DSVLQNLIDL LSRRYFESME DYNSALHAHI
EALEDKLTFL KNFIGFAKFL GVEERELGDL LAHVQVVALN AARLSYKCLF YKEDEEMHDP
RMCSIISELL EKINPVDLQV YETYVKVLKA PKSPESLLTT QTDMQILKNF NDSLISSLWE
LLWCRTSFAV SVKDQMKRLY EGLRFLRSIL NEAQENMNEL NDKIVAVISE AGIVIFSLFL
NGVKEVEVDS LVVGESADCC AMLVTTNNSV KLIVDVSGSR ISGSLPHYHS FRGQEVRKTT
RFKPSRGRAP ITREIVVGLE DEAQKVINRL NRGSTKLQIV PIVGMPGLGK TTLAKKVYND
PRVQGHFRII LWCTVSQEYN LKNLLVQILS SVGIQGRVNE EHKVLDEIDL MLYLKRLLLR
NRYLVVLDDV WDIGVWHGLR HSFPDDSTGS RILITTRESS VASEVRIGVD SVEHHNLREL
TKEESWELLQ KKVFGEADCP QPLRMLGEQI ARNCKGLPLT IVIIAGILST IEDEAWSDVA
DRLTSAIVYD QCKYILELSY RHLPHYLIPC LLYFGAFRED QEIETEKLTR LWIAEGFVSV
EELVQDTEPK RLEDLAEEYM MDLIGRNLVM VAKQGHTGGV KTCRIHDLLH EFCKDRAKKE
NFLQVLRGYG ELSTFNEHPY LERLSIWSKV EQFKKSRLFC PQLCSLLLFS QIEESDSFMA
DMSFVFGIYK KLRVLDLEQI FLRHKVFPRE VEALVELRYL GVQGAMSSIP STIDKLSNLE
TFVVIAESGT VSFPDTIWNM TKLRHLHVVG WNVSCSLPSE NLENTSDLWN LDTLSTLTVT
LDDRAANIMR KVPNVRQLKI QLSAAECSVG CCNLSHLSSL EALEVSAESL PSNPVEFSFP
LNLKELVLGG LHLPWSKISV IQELPELEVL ILLGESFVGE RWELTAGGFP KLMCLSLENL
DVVKWEDATG GDDVFPYLRK LRLIGVLELK EVPSCLGQSE SLEEIEVRDC NDSLKESVRK
IWEDMGYEDL KIIID
//
