ID A0A068V9Q6_COFCA Unreviewed; 272 AA.
AC A0A068V9Q6;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Bidirectional sugar transporter SWEET {ECO:0000256|RuleBase:RU910715};
GN ORFNames=GSCOC_T00000674001 {ECO:0000313|EMBL:CDP17204.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP17204.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the membrane. {ECO:0000256|RuleBase:RU910715}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU910715};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU910715}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000256|ARBA:ARBA00007809, ECO:0000256|RuleBase:RU910715}.
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DR EMBL; HG739232; CDP17204.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068V9Q6; -.
DR EnsemblPlants; CDP17204; CDP17204; GSCOC_T00000674001.
DR Gramene; CDP17204; CDP17204; GSCOC_T00000674001.
DR InParanoid; A0A068V9Q6; -.
DR OMA; LYFMYYK; -.
DR PhylomeDB; A0A068V9Q6; -.
DR Proteomes; UP000295252; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1280.290; -; 2.
DR InterPro; IPR047664; SWEET.
DR InterPro; IPR004316; SWEET_rpt.
DR PANTHER; PTHR10791:SF142; BIDIRECTIONAL SUGAR TRANSPORTER SWEET16; 1.
DR PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910715};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU910715};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU910715}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 66..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 126..147
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 185..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
SQ SEQUENCE 272 AA; 29500 MW; F1A62C61F91CA5AF CRC64;
MASFSVILGI IGNVISILMF LSPVKTFRRI VKKKSIEDFK GVPYITTLLS TSLWSFYGIL
KPGGLLVLTV NGAGAILHII YVTLFLIYAP KDVKVKSLKL VAIVDVGFFG VVVAVTLLAL
HGSLRLTVVG LLCTGMTIGM YASPLSVMRT VIKMKSVEYM PFFLSFFQFL NGGVWAAYAV
LVKDIYLGVP NGIGFILGLA QLLLYVFYKN KYASKSKEAM EDGGGGSAHP IKGVIQMEDF
DNNEKMKTIS LNQGAFGSTG SKDLELGVKD NL
//
