ID A0A068VDP2_COFCA Unreviewed; 499 AA.
AC A0A068VDP2;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSCOC_T00003928001 {ECO:0000313|EMBL:CDP17803.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP17803.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
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DR EMBL; HG739264; CDP17803.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068VDP2; -.
DR STRING; 49390.A0A068VDP2; -.
DR EnsemblPlants; CDP17803; CDP17803; GSCOC_T00003928001.
DR Gramene; CDP17803; CDP17803; GSCOC_T00003928001.
DR InParanoid; A0A068VDP2; -.
DR OMA; ATEPGMW; -.
DR PhylomeDB; A0A068VDP2; -.
DR Proteomes; UP000295252; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11073; CYP76-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR47950:SF4; CYTOCHROME P450 76C4; 1.
DR PANTHER; PTHR47950; CYTOCHROME P450, FAMILY 76, SUBFAMILY C, POLYPEPTIDE 5-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 499 AA; 56551 MW; DEC6FEDD5FE82F3C CRC64;
MALFDALLWL ALFFVIWAST YFLVSELRSR RIARLPPGPY PIPIFGNILD VGQKPHESFA
RLSKIYGPLM YLKLGSKRTV VVSSPTIASE VLQKYDQLFS GRGVANAVQA LDHHKASIVF
LPASSQWRNL RKICKEQLFS LQKLDASQGV RREKLQELCD YLQRCSVSRK IVNVSDAAFT
TSLNLISRSL FSVDFANYDS NSSQELKGIV WGIMKNAGAP NLADYFPVLQ MIDPQGIRRG
MTFYMQRLFA IFDDVIDERL QVRGTSETKK NDLLEGLLDH SIKNESEFCR NDLKHLLLDL
FLAGTETASV TVEWAMAELL RSPDKIANIR AELKEVIGKK EGVQESDISR LPYLQAVIKE
TFRLHPPAPF LIPHKADEDV EINGFIVPKN TEVLVNVWAS GRDPTIWSNP ENFEPERFLG
SDIDVRGQHF ELIPLGAGRR ICPGLPLGYR MVHLMLASFI YNIDWKLEDG MKPEDLDMEE
KFGLTVQKAW PLKAIPVKL
//
