ID A0A068VHM5_COFCA Unreviewed; 894 AA.
AC A0A068VHM5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=DH200=94 genomic scaffold, scaffold_964 {ECO:0000313|EMBL:CDP20176.1};
GN ORFNames=GSCOC_T00009614001 {ECO:0000313|EMBL:CDP20176.1};
OS Coffea canephora (Robusta coffee).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Gardenieae complex;
OC Bertiereae - Coffeeae clade; Coffeeae; Coffea.
OX NCBI_TaxID=49390 {ECO:0000313|EMBL:CDP20176.1, ECO:0000313|Proteomes:UP000295252};
RN [1] {ECO:0000313|Proteomes:UP000295252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DH200-94 {ECO:0000313|Proteomes:UP000295252};
RX PubMed=25190796; DOI=10.1126/science.1255274;
RA Denoeud F., Carretero-Paulet L., Dereeper A., Droc G., Guyot R.,
RA Pietrella M., Zheng C., Alberti A., Anthony F., Aprea G., Aury J.M.,
RA Bento P., Bernard M., Bocs S., Campa C., Cenci A., Combes M.C.,
RA Crouzillat D., Da Silva C., Daddiego L., De Bellis F., Dussert S.,
RA Garsmeur O., Gayraud T., Guignon V., Jahn K., Jamilloux V., Joet T.,
RA Labadie K., Lan T., Leclercq J., Lepelley M., Leroy T., Li L.T.,
RA Librado P., Lopez L., Munoz A., Noel B., Pallavicini A., Perrotta G.,
RA Poncet V., Pot D., Priyono X., Rigoreau M., Rouard M., Rozas J.,
RA Tranchant-Dubreuil C., VanBuren R., Zhang Q., Andrade A.C., Argout X.,
RA Bertrand B., de Kochko A., Graziosi G., Henry R.J., Jayarama X., Ming R.,
RA Nagai C., Rounsley S., Sankoff D., Giuliano G., Albert V.A., Wincker P.,
RA Lashermes P.;
RT "The coffee genome provides insight into the convergent evolution of
RT caffeine biosynthesis.";
RL Science 345:1181-1184(2014).
CC -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC races carrying the avirulence gene Avr1. Resistance proteins guard the
CC plant against pathogens that contain an appropriate avirulence protein
CC via an indirect interaction with this avirulence protein. That triggers
CC a defense system including the hypersensitive response, which restricts
CC the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; HG740048; CDP20176.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068VHM5; -.
DR EnsemblPlants; CDP20176; CDP20176; GSCOC_T00009614001.
DR Gramene; CDP20176; CDP20176; GSCOC_T00009614001.
DR InParanoid; A0A068VHM5; -.
DR OMA; RSEFQIF; -.
DR PhylomeDB; A0A068VHM5; -.
DR Proteomes; UP000295252; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000295252}.
FT DOMAIN 51..123
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 194..430
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 894 AA; 103409 MW; 9FC67459A3F47555 CRC64;
MNENVVEEKK FLLSEVIGKI ERFLEVVKKF YVYIPEASEF YSLRTHGIGY IDFILENLKK
MLKQNCKFVP FVKHKVVMVQ EELQSLRTFL TDKMDGQNEH EELKDLWRRT INVAYHAEHV
TDLSLISCSC FWYSIICLST VIQEIKITKT EIENIGNKHM KKPVILIANM NSMHPFAAQA
SNSRIDEAVI GFDDEAETII NRLTRGSEQL EIVSIIGMPG QGKTTLAKKV YNHPSICYHF
IQCVWCCVSQ EYEYRSALLE MLCNVTELSR HDTSEMSNDE LANRLRKCLI GRSYLIVMDD
IWDIRPWSEL KRSFPDNNNG SRILFTSRIQ KFSWQDECKC YFHTLRPFHE EECWQLLKQK
TFHKDECPQD LVEVGMEIAR KCKGLPLSIV LVAGILSRSK NSLYWWKQIA FNLSSSHPTE
GSMDILELSY KHLPDHLKPC FLYLGAFSGG QKIRARKMTL LWISEGFIGR TDQRRLEDVA
MECLMDLINH SLVIVSERSS DGGIKGCQVH NLLREFCIMK AKEEKFLQLI YQYDFDKDPS
DGHDIDMHRL CFHGSLFYFA DSHRICSPVH SIIFAYGMEF VDYCFFRTFR LLKVLDMERL
YLKGSDLDAL MLLVHLRYLA ISGSIRRLPS SIANLWNLET LIVIRRLPWS IDLPDTIWQM
KSLRHVNARA FANVSLGDYE FEELCQLENV HTFSTVLCHG RDTEILLRRL PRLRKLSCII
PESGKHQVGS CKVLDFSILS ELEALDLSCM GGTEFSTPKI PAFEFPKVLK KLTLFKCFLP
TAAISAIGQL PNLVVLKLRN IDFAKHILYV EDGEFLNLKF LAMHHSEFER WAVPDEPFPS
LENLVLTDCT KLKEIPSSFA DISTLKMIKI RGCCPSIISC CFFFLVNTCE ILPK
//
