ID A0A068Y5N4_ECHMU Unreviewed; 369 AA.
AC A0A068Y5N4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE SubName: Full=Thioredoxin domain containing protein 15 {ECO:0000313|EMBL:CUT98887.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CUT98887.1};
RN [1] {ECO:0000313|EMBL:CUT98887.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CUT98887.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN902845; CUT98887.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068Y5N4; -.
DR STRING; 6211.A0A068Y5N4; -.
DR eggNOG; KOG2640; Eukaryota.
DR OMA; DEYLQFR; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd02961; PDI_a_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR042418; TXNDC15.
DR PANTHER; PTHR14684:SF2; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15; 1.
DR PANTHER; PTHR14684; UNCHARACTERIZED; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..369
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009741550"
FT TRANSMEM 297..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 122..268
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 369 AA; 42244 MW; D8444E4C1AC34D33 CRC64;
MWVASFISAS FFLNLLLSVS HSASEETSTV IKSGNLTLTS ENPRNRVNAT LSDAQNDAGD
PRDQSNDTAH QVYVDASSNW RKGVDNFESG EKVITRCRLR LVNYWNYTQG RANVVPGYEF
GTVVGVSHSS YSHPYGVFSG SVNPYRHNLR LFSLLNPFFS HLRGNYVFVK NKSSARLIDS
PCNLVFIFAQ WCPFSMRAAP YINALARAFP QLPVIAIDVD EYLQFRWSLR VFYVPKIKIF
VGDHVYKEFN GTETDLDELA DFVWQNLRQI PQGPLELRRE DFFGPIPTQL VSRPSDYRLQ
VVWVIFLVSS AYFFGYFVDC RGIRRHITAA LKLMSHLLDH RRRRRRNVAA HAALPPPSLP
AIRYHSHTE
//
