ID A0A068Y5Z6_ECHMU Unreviewed; 1876 AA.
AC A0A068Y5Z6;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 8 {ECO:0000256|ARBA:ARBA00020983};
DE AltName: Full=Component of oligomeric Golgi complex 8 {ECO:0000256|ARBA:ARBA00031347};
GN ORFNames=EmuJ_000485100 {ECO:0000313|EMBL:CDS37591.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CDS37591.1};
RN [1] {ECO:0000313|EMBL:CDS37591.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CDS37591.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the COG8 family.
CC {ECO:0000256|ARBA:ARBA00006419}.
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DR EMBL; LN902843; CDS37591.1; -; Genomic_DNA.
DR STRING; 6211.A0A068Y5Z6; -.
DR eggNOG; KOG2069; Eukaryota.
DR OMA; YPIFLAN; -.
DR GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR007255; COG8.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR21311; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8; 1.
DR PANTHER; PTHR21311:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8; 1.
DR Pfam; PF04124; Dor1; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 858..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1015..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1073..1099
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1521..1661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1692..1730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1760..1784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1826..1876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..928
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1045
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1521..1576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1578..1619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1826..1845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1846..1869
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1876 AA; 204282 MW; 29F91C9C22AEE2BA CRC64;
MGEDSLTDLL NLDAKVEVEK LIQMLLLSSD VESSVSADPQ FADCISKLSH LRLDELAATP
KRIQMEEDSI RHKTEQLAVE NYPIFLANAN TSRDVHREFL SISESNVNLL ASIAGVSSAA
QTIFNNIGKN ASAFRVSAKF VQKYTQILDF LELPQLMDTC IRNGYCQDAL NILSHTKRMT
KKYGRTVPIV RMVGLQAQEI SGQLFSQLCK QLREPVTLPV CLKVVIYLRQ FEAFTEQELR
LNFLQARAIC IKDQLEFALT KPIGLSSFDS SSSTQSAHIS GHQQAEYRAF IRAMRRIEVT
RVQLFDSITQ YRAVFADEEA YSSKLTDPHR HPVLADISPL HIDETALTLR GLATNGIDYL
GPSTEASLFH SWLVHQVGIF LDGLDGDLNA LLSLPHFTPS EISDRIRLAM ANDSITLDSV
DAPTTFQQIH SVMTQALYFG RSFARIGCDF RAHLGAIFSR ATLNYFEALL TNALIELSAT
LELWPWELSE LPFMTNQPES TSSDEFSVPM AIALHPPIAF FCNRLLTAFN GLCICCPVGL
RDGVLSASIR ILSGAAEAIV AAHKSRQLDS AAARAQSSNL ASVFAHVAVP HLLSCLLEYI
FGGDAAAHLW QLRLEGEEEV PSTSQTVSLL ARRVCAPIFV VWGQLSTGPL RAGDTVKQSV
IPDTDEVRPT SDAHASLLTT ALEKRQPSQF QHGEPKALAS LTEQSNDLSI AKGAPHSLEL
SLLQKEEVEF ESKAVAAHSA GFAPVFEVEK NKSEVLEKPN ASILAKNEVG WEAASSYPEN
DGPCAVPEDL KTARLDSSAL ELVEPSLSST EKCTISDTDA HLASMQKSKP EAVSSTLPAT
EVEGWNSHLG IWPHEEAREE AAPCQMTEPN QEEVLHGDVE APPKSPVSLS PQEPRMKNFS
APELAVPPVT KATVKDSQED KEGKEVNEES AAVLSSKLSS TAIEESGQQD VETRAEIESI
DRLSLDAYRS AETMTIEGNT TAENRFNNHY STLLEMEGDQ SDNDTALQPY HPHSLLRKNQ
PSMEDGEKCV QSSSTSHNSA AKSSEASVVK LKLTLPNDTP CDKHFLSVQK TPPFVEEGDS
FPTDSKGEGL PSVPKSPSLK GAFLEQPKLG LTDPPTEKER VFGGLQQGFD ILDNREPQPS
MKDNGISPSH ELISPPSVKK LENGDNNSSI LFVLDDNANE LKTPATVSVP PMITTCPTSV
SRVSETLNEP ADWNDEKNDG DDGNLIGHST TNKKVCVSAA SNEQDIDIQA NHESLFPTSD
QTNFSNQEVT TVLSVKEESA SKDDSISLSD LGSDDASELS ASAEISVPAM VTICPTSTLG
HPDADNGLAN WIDVDVGGEA DVNNQKAEYL EEEFTINKND KVLTNIDDLI VNKPEEREMD
GTVATDMQLP VVEQAVNKGS GEELVEAVNI GARDVERPIA LYSSDLDTSP ESRLIEDNNG
KESSADSGFE VNAKLSVNEN VDITGIGNLG ESAIVDQKVE AVGTVEDEFA NWKGGCEADT
DPSDFASLQN LEIDVQSVAK TDSLANNSKE ESSDVANPDG TPTNPDTEVL LPSVTIASHT
TKATDLDGTG KSETSPEKLA SFDADWREGD NAWGEDADTN INDEEKLNLH TDDKPVESDS
NLIQRNAEGE LETARSSEID ANVSANEPRD WDFYGNSPPT KQIDFESLEE EEIKAQTPTS
SNEWKTEVER VEGNETHFEK QAINAGTSAE KRLEEGQSPL SAKPANNADL GEDETTWAED
ADISVNVIQE HHDLRRFRSD SALPGNTYCE KEDLPTTNIA SAPPFSNAYI SQSKTAYSSR
TVVDRQEKQL AVGGTVASTP RIILKSSSVH PESSEVQAVD ADQSKAVNDN FKDSSKSPDE
AKVDDVGNNE GWDVDF
//
