ID   A0A068Y620_ECHMU        Unreviewed;       395 AA.
AC   A0A068Y620;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   22-FEB-2023, entry version 31.
DE   RecName: Full=NAD(+) kinase {ECO:0000256|ARBA:ARBA00012120};
DE            EC=2.7.1.23 {ECO:0000256|ARBA:ARBA00012120};
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211 {ECO:0000313|EMBL:CUT99037.1};
RN   [1] {ECO:0000313|EMBL:CUT99037.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23485966; DOI=10.1038/nature12031;
RA   Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA   Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA   Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA   De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA   Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA   Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA   Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA   Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA   Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA   Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA   Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA   Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA   Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT   "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL   Nature 496:57-63(2013).
RN   [2] {ECO:0000313|EMBL:CUT99037.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD kinase family.
CC       {ECO:0000256|ARBA:ARBA00010995}.
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DR   EMBL; LN902845; CUT99037.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A068Y620; -.
DR   STRING; 6211.A0A068Y620; -.
DR   eggNOG; KOG4180; Eukaryota.
DR   OMA; QCVSHVA; -.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR   GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR002504; NADK.
DR   PANTHER; PTHR13158; -; 1.
DR   PANTHER; PTHR13158:SF5; NAD KINASE 2, MITOCHONDRIAL; 1.
DR   Pfam; PF01513; NAD_kinase; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CUT99037.1};
KW   NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ   SEQUENCE   395 AA;  43849 MW;  BA1261857CA2BCFD CRC64;
     MLGRFLCPFL RRGSIFSLKV SCRFSLSSNI RNHFEKVLIV CKTTGIDCGG DTYPVIHSFP
     FEKHVAKKSC SIVDELMRCF TKCGVKVDAV NYKEYDFKHA KSADLVVSVG GDGTFLTAAV
     RITEKDKPII GINSNPVSSE GSLCLPRHWH KKIPVIVDRL VNEQFSRRFR QRIRLLVSTP
     SAQLIPLDTV TPRLFESRAP HSRPSDKDSG EDPAVAALPP AYLLPVRVLN DVFISACLNT
     RVSRYEISVE EATPVTQKSS GLLVCTGTGS SSWYRSLHQV DVHLVARLLS LASDSHPDVT
     AAAEVAERFN RDLVFPPDSP LMAYSVREII TNHVFKFGSP RGFAKKLRVV SRMEDAYLCI
     DGWLALPFED GDSVELSIHP DDALCVIDFH DSTLG
//