ID A0A068Y9V6_ECHMU Unreviewed; 804 AA.
AC A0A068Y9V6;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Eukaryotic release factor 3 erfs {ECO:0000313|EMBL:CUT99327.1};
OS Echinococcus multilocularis (Fox tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX NCBI_TaxID=6211 {ECO:0000313|EMBL:CUT99327.1};
RN [1] {ECO:0000313|EMBL:CUT99327.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23485966; DOI=10.1038/nature12031;
RA Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL Nature 496:57-63(2013).
RN [2] {ECO:0000313|EMBL:CUT99327.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Y., Guo Z.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; LN902845; CUT99327.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068Y9V6; -.
DR STRING; 6211.A0A068Y9V6; -.
DR eggNOG; KOG0458; Eukaryota.
DR OMA; CFETEHR; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd04093; HBS1_C_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF188; HBS1-LIKE PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 335..566
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 228..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 86781 MW; BF69196939B6AD76 CRC64;
MTVRIVWSMR SRNGEAPEYY NDYHDLVPSS VEEENSITPG TDLFCPLSNK PLKINASEFP
EEDAIGTTPL ANAVSSHHND EVVDSAVSIE FDNLVLEDIS DPLRGALYST SSAFQPFGSD
GGLTDFAEFD FSSLAKLTEG PKLATASTGS TKHLNSASSV SLNEEKSKVD AVASDSIQSC
QKISPLGHAF AQSRSSIPRR DLQFLNLIVE IRRPRTFLFL HNPPSSKPPD AFKFDTPQPV
QFDSPSDLKM SSNVLPKTRT KPSKLQRNLY PSKDPSGKPS VEPPSSLPLV ETSTAATRLP
KVASEAKVST QPAKPIDRSS LFHAYQKKIS SGKEKDIINL LVVGHVDAGK STLMGNVLCQ
LGHVSEKQLA KYQWEAQKIG KASFAYAWVL DQTSEERSRG ITMDIAQIAF ETHSKRVVLL
DAPGHRDFVP QVIGGAAQAD VALLVVNATS GEFETGMQLS GGQTQEHARL VRLLGVSRLI
VAVNKMDTVS WSQSRFEEIR TVMMRMLKTI NQPDVVFCPV SGLYGINLLH SSDTPPERDI
QHLAPWYSGP CLLDIIDSLD KVERPVDAPF RFVVSDIFKP IGSSVPIVAG RVVSGAVSAG
VNLPTSKIIC LPSGQTGTVR SIRSLAAVPS DGGGSGTGVL DIILPYAFAG DQVGLMLSGL
DADLALTPGD VICDPDPPLA SVTTRLRAKV LIFDVQQPIT RGYPVIFYYH CSSVPAVITK
LLSATVKDEE RGKKDVVKPR CLLGRCTAEI ELALESPVCV EIYDVCKPLG RFVLRVGGES
IAGGTIVALK RGKIGSVPVQ SEVK
//
