ID A0A069JK19_9ACTN Unreviewed; 416 AA.
AC A0A069JK19;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Polyketide beta-ketoacyl synthase {ECO:0000313|EMBL:KDQ65424.1};
GN ORFNames=DT87_31600 {ECO:0000313|EMBL:KDQ65424.1};
OS Streptomyces sp. NTK 937.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1487711 {ECO:0000313|EMBL:KDQ65424.1, ECO:0000313|Proteomes:UP000027475};
RN [1] {ECO:0000313|EMBL:KDQ65424.1, ECO:0000313|Proteomes:UP000027475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTK 937 {ECO:0000313|EMBL:KDQ65424.1,
RC ECO:0000313|Proteomes:UP000027475};
RA Olano C., Cano-Prieto C., Losada A., Mendez C., Salas J.A.;
RT "Draft genome sequence of marine actinomycete Streptomyces sp. NTK 937,
RT producer of the benzoxazol antibiotic caboxamycin.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDQ65424.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JJOB01000003; KDQ65424.1; -; Genomic_DNA.
DR RefSeq; WP_028441964.1; NZ_JJOB01000003.1.
DR AlphaFoldDB; A0A069JK19; -.
DR OrthoDB; 416758at2; -.
DR Proteomes; UP000027475; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 6..410
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 416 AA; 43511 MW; EF7C7F1CB1002C87 CRC64;
MSNPAHRRSV ITGIGVVAPN GTGTGAFWKQ TQEGVSVLDR VTREGCENLP LRVAGEVRDF
DPVASVEERY LVQTDRFTHY AMAAADLALD DARLGRADYE DTPFKVGVVT AAGSGGGEFG
QRELERLWGQ GPRFVGPYQS IAWFYAASTG QISIRGGFKG PCAVVASDEA GGLDALMHAA
RSVRGGTDAL VVGAAEAPLA PYSVVCQLGY EDLSACDEPT RAYRPFTADA CGFVPAEGGA
MLVVEEETAA RGRGARVRAE IAGHCATFTG AGRWEQSRQG LARAVEGALR EAGCAPEEID
VVFADALGVP AADRAEAGAL ADALGAHGRR VPVTAPKTGI GRAYCGAPVL DVSAAVLAME
HGLIPPTPNV FEVCHDLDLV TVRARPAQLR TALVLSRGLM GSNSALVLRR PTDTPD
//
