ID A0A069JRV5_9ACTN Unreviewed; 608 AA.
AC A0A069JRV5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=DT87_09270 {ECO:0000313|EMBL:KDQ67401.1};
OS Streptomyces sp. NTK 937.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1487711 {ECO:0000313|EMBL:KDQ67401.1, ECO:0000313|Proteomes:UP000027475};
RN [1] {ECO:0000313|EMBL:KDQ67401.1, ECO:0000313|Proteomes:UP000027475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTK 937 {ECO:0000313|EMBL:KDQ67401.1,
RC ECO:0000313|Proteomes:UP000027475};
RA Olano C., Cano-Prieto C., Losada A., Mendez C., Salas J.A.;
RT "Draft genome sequence of marine actinomycete Streptomyces sp. NTK 937,
RT producer of the benzoxazol antibiotic caboxamycin.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDQ67401.1}.
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DR EMBL; JJOB01000001; KDQ67401.1; -; Genomic_DNA.
DR RefSeq; WP_037877291.1; NZ_JJOB01000001.1.
DR AlphaFoldDB; A0A069JRV5; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000027475; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..608
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001666530"
FT DOMAIN 52..391
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 430..608
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 608 AA; 63461 MW; 694F12FF9453925A CRC64;
MHHRTSRRTL LAATAATAAA AATGVVAVPG TAQASGTSTD SRLKRLIARM SLEEKVGQLF
VMRVYGHSAT APDQADIDAN LDEIGVRTAA ELIARYHVGG IIYFTWAHNT RDPHQIADLS
NGIQRAALAQ PTPLPLLIST DQEHGIVCRV GEPATLMPGA MALGAGGSRS DARTAARIAG
AELAALGINQ NYAPDADVNV NPANPVIGVR SFGSDPQSVA GLVAAQVKGY QSAQVASTAK
HFPGHGDTST DSHTGLPSIQ HTREQWAELD APPFRAAVAA GIDSIMTAHI VVPALDPSED
PATLSRPILT GILREELGYD GVVVTDSLGM EGVRTKYGDE RVPVLALQAG VDQLLNPPDL
SVAWNAVLAA VKSGEISEAR IEESILRILR LKSKLGLFRD PYVTRRGVDR TVGVKEHLAT
ADRIAERTTT LLAHTGALLP LSRRTHRNVL VVGADPASPS GTTGPPTTTL AAAFEELGFR
ATALPTGTAP SPATIEAAVT AAAGKDAVVV GTYGVTATSS QRTLVAALAA TGVPVICLAI
RNPYDIAHLT GTGYAASLAT YSWTDVELRA AVRVIAGRAR PKGRLPVPVR RADAPEQTLY
PVGFGLSY
//
