ID A0A069JYD3_9ACTN Unreviewed; 598 AA.
AC A0A069JYD3;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Peptide synthetase {ECO:0000313|EMBL:KDQ70064.1};
GN ORFNames=DT87_23630 {ECO:0000313|EMBL:KDQ70064.1};
OS Streptomyces sp. NTK 937.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1487711 {ECO:0000313|EMBL:KDQ70064.1, ECO:0000313|Proteomes:UP000027475};
RN [1] {ECO:0000313|EMBL:KDQ70064.1, ECO:0000313|Proteomes:UP000027475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTK 937 {ECO:0000313|EMBL:KDQ70064.1,
RC ECO:0000313|Proteomes:UP000027475};
RA Olano C., Cano-Prieto C., Losada A., Mendez C., Salas J.A.;
RT "Draft genome sequence of marine actinomycete Streptomyces sp. NTK 937,
RT producer of the benzoxazol antibiotic caboxamycin.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDQ70064.1}.
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DR EMBL; JJOB01000001; KDQ70064.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A069JYD3; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000027475; Unassembled WGS sequence.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 521..596
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 500..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 63938 MW; A4AFC8E3F7DF4D89 CRC64;
MNTVSELFES VVTESGDAPA VVFGESVLDY AELNARANRL ARRLIAAGVG PDALVAVAVP
RSARLVVAVL AVLKAGGAYL PLDPDYPAER LTHMVVDARP VLLLRTDGVT SLHLDVPELV
LDDPSFEALC EGERGDDIAA GERTAPLVPA HLMYVIYTSG STGVPKGVAV SHTGVTDLVS
TQVRLYGVGR GDRILQWASF SFDAWFWDFA LALLNGATLV MAEQHALMPG ESLRETMLTY
SIDHAVLPPV ALGITDSEGL LVGGTITSTG DVCTRALAEE WSKGRRLYNA YGPTEVTVGA
SIGGPVKGVQ DEVTVGTPWD GGVVHVLDER LRECPDGQEG ELFLAGSGVV RGYLNRPGLT
ASRFVADPYG PPGSRMYRSG DRGRHEADGE LYFTGRIDNQ VKMRGFRVEL GEIETRLESH
PAVEIVVAVV GGQDAATEHI VAYVRTSDRH EVTEAQLRAH ARDALPEHMV PTHVVVLDRF
PTLPNGKIDR KELAERAVRA PAGGHGTPPD PAPAAGEGGA GEAASYEEGL CRMVGEILQV
PEVTPKDNFF DLGGHSMLAA KLAGRMRKEL GVTVPMRSMF EAQSLAELAQ VMERVKRG
//
