ID A0A069NL12_9BURK Unreviewed; 577 AA.
AC A0A069NL12;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Dihydroxy-acid dehydratase {ECO:0000313|EMBL:KDR29138.1};
DE EC=4.2.1.9 {ECO:0000313|EMBL:KDR29138.1};
GN ORFNames=BG57_18575 {ECO:0000313|EMBL:KDR29138.1};
OS Caballeronia grimmiae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=1071679 {ECO:0000313|EMBL:KDR29138.1, ECO:0000313|Proteomes:UP000027439};
RN [1] {ECO:0000313|EMBL:KDR29138.1, ECO:0000313|Proteomes:UP000027439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R27 {ECO:0000313|EMBL:KDR29138.1,
RC ECO:0000313|Proteomes:UP000027439};
RA Liu X.Y., Li C.X., Xu J.H.;
RT "Draft Genome Sequences of Four Burkholderia Strains.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC {ECO:0000256|ARBA:ARBA00006486}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDR29138.1}.
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DR EMBL; JFHE01000032; KDR29138.1; -; Genomic_DNA.
DR RefSeq; WP_035968805.1; NZ_JFHE01000032.1.
DR AlphaFoldDB; A0A069NL12; -.
DR STRING; 1071679.BG57_18575; -.
DR eggNOG; COG0129; Bacteria.
DR OrthoDB; 9807077at2; -.
DR Proteomes; UP000027439; Unassembled WGS sequence.
DR GO; GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR InterPro; IPR042096; Dihydro-acid_dehy_C.
DR InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR InterPro; IPR037237; IlvD/EDD_N.
DR PANTHER; PTHR43183:SF2; DIHYDROXY-ACID DEHYDRATASE; 1.
DR PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00920; ILVD_EDD; 1.
DR SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR PROSITE; PS00886; ILVD_EDD_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:KDR29138.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
SQ SEQUENCE 577 AA; 62626 MW; 44462F2DD5D915FA CRC64;
MTIRKKPEAL RSHRWYGVND LRSFGHRSRT AQMGYHPSDY MGKPVIAIVN TWSEINPCHT
HFKQRVEEVK RGVWQAGGFP VEMPVMTLAE PFQKPTTMLY RNFLAMEVEE LLRSYPFDGC
VLMGGCDKTT PGLLMGAISM NLPAIFLPAG PMLRGNWNGR TLGSGSDTWK YWAELRAGRI
TEDEWKGVES GIARSPGHCM TMGTASTMTS AAESLGLTLP GFASIPAVDS RHAQFASLTG
QRIVEMVWTD LKPSDVLTAK SFDNAVTTVL ALSGSTNAIV HLVAVARRAG VPLTTARFDE
LARVTPVIGN VRPAGKYLME DFFYAGGLRA LLAELGDLID GAQLTVNGAT LGENIAGAEI
FDDDVIRRRD NPLVPNDGLA VLTGNLAPDG AVIKPAAMEA HLLKHRGPAV VFRDYADLAA
RIDDEALDVT ADSVIVLQHA GPVGAPGMPE WGQLPIPQKL LKQGVRDMVR ISDARMSGTS
YGACVLHVAP ESFVGGPLAL VRDGDIVELD VPARRLHLDV GDDELAARRA AWAPPKRPFE
RGFGVMHQLH VTQANRGCDF DFLEERSVAD GGEPEIH
//
