ID A0A069PF92_9BURK Unreviewed; 398 AA.
AC A0A069PF92;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KDR38509.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:KDR38509.1};
GN ORFNames=BG61_39690 {ECO:0000313|EMBL:KDR38509.1};
OS Caballeronia glathei.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=60547 {ECO:0000313|EMBL:KDR38509.1, ECO:0000313|Proteomes:UP000027466};
RN [1] {ECO:0000313|EMBL:KDR38509.1, ECO:0000313|Proteomes:UP000027466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 50014 {ECO:0000313|EMBL:KDR38509.1,
RC ECO:0000313|Proteomes:UP000027466};
RA Liu X.Y., Li C.X., Xu J.H.;
RT "Draft Genome Sequences of Four Burkholderia Strains.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDR38509.1}.
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DR EMBL; JFHC01000087; KDR38509.1; -; Genomic_DNA.
DR RefSeq; WP_035928769.1; NZ_JFHC01000087.1.
DR AlphaFoldDB; A0A069PF92; -.
DR STRING; 60547.GCA_000751215_01802; -.
DR Proteomes; UP000027466; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:KDR38509.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027466};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KDR38509.1}.
FT DOMAIN 5..267
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 275..396
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 354
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 384
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 398 AA; 42493 MW; A6C37B437F8DEDE5 CRC64;
MRRAAIVAPV RTAVGTFGGS LRDVPVETLT TAVIEAVLAR TRIDPGRIDD VVFAQSYANS
ETPCIGRWAA LHAGLPVSVP GLQIDRRCGS GLQSVVTAAM MVQSGAADVV LAGGVESMSN
IEYYSTDMRW GKRSGSVRFH DRLERGRERS QPEARFGYIS GMVETAEHLA RDYGITRAEA
DAYAARSHQR AAAAWEGGRF DDEVVPLAVP QKKGEPLVFT RDEGIRAGTT VDTLAKLKPL
MNDGTVTAGN ASQQNDAAAA CLIVAEDKLD ELELAPLGYL AGWAAAGCEP SRMGIGPVPA
VERLFARTGF TFDRIDLVEL NEAFAAQVLA VLKGWQWNDP ERLNVNGSGI SLGHPIGATG
VRMLATLLHE LRRRGARYGL EAMCIGGGQG MAAIFESA
//
