ID A0A071LPX6_9ENTR Unreviewed; 386 AA.
AC A0A071LPX6;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:KEA50355.1};
DE EC=2.5.1.48 {ECO:0000313|EMBL:KEA50355.1};
GN ORFNames=DT73_24240 {ECO:0000313|EMBL:KEA50355.1};
OS Mangrovibacter sp. MFB070.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Mangrovibacter.
OX NCBI_TaxID=1224318 {ECO:0000313|EMBL:KEA50355.1, ECO:0000313|Proteomes:UP000027726};
RN [1] {ECO:0000313|EMBL:KEA50355.1, ECO:0000313|Proteomes:UP000027726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MFB070 {ECO:0000313|EMBL:KEA50355.1,
RC ECO:0000313|Proteomes:UP000027726};
RA Joseph T.C., Varghese A.M., Baby A., Reghunathan D., V M., Lalitha K.V.;
RT "Draft Genome Sequence of Mangrovibacter spp. MFB070 a Nitrogen-fixing
RT Bacterium Isolated from an Aquaculture Farm.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEA50355.1}.
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DR EMBL; JJMI01000052; KEA50355.1; -; Genomic_DNA.
DR RefSeq; WP_036115855.1; NZ_JJMI01000052.1.
DR AlphaFoldDB; A0A071LPX6; -.
DR eggNOG; COG0626; Bacteria.
DR Proteomes; UP000027726; Unassembled WGS sequence.
DR GO; GO:0003962; F:cystathionine gamma-synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0102028; F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine); IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR011821; O_succ_thio_ly.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR02080; O_succ_thio_ly; 1.
DR PANTHER; PTHR11808:SF75; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000027726};
KW Transferase {ECO:0000313|EMBL:KEA50355.1}.
FT MOD_RES 198
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 386 AA; 41490 MW; 7804C56D45A98A30 CRC64;
MTRKQATIAV RSGLNNDEQY GCVVPPIHLS TTYNFTDFNS PREHDYSRRG NPTRDVVQRT
LAELEGGAGA VMTNTGMSAI HLLTAIFLNP GDLLVAPHDC YGGSYRLFDS MAKRGCYRVQ
FVDQNDEAAL ESALAQNPKL VLIESPSNPL LRVVDIAKIC QAAKAAGAIT VVDNTFLSPA
LQNPLALGAD LVVHSCTKYL NGHSDVVAGA VIAKDADMAT ELAWWANNIG VTGSAFDSYL
LLRGIRTLAP RVELAQRNAL AIVDYLKKQP LVKRLYHPSL PENPGHDIAV RQQKGFGAML
SFELDGDEQT LRRFLKGLSL FTLAESLGGV ESLISHAATM THAGMSAEAR AAAGISETLL
RISTGIEDGD DLIADLENGF RAASEG
//
