ID A0A072NCF6_9DEIO Unreviewed; 447 AA.
AC A0A072NCF6;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Hemolysin {ECO:0000313|EMBL:KEF35379.1};
GN ORFNames=RDMS_02515 {ECO:0000313|EMBL:KEF35379.1};
OS Deinococcus sp. RL.
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=1489678 {ECO:0000313|EMBL:KEF35379.1, ECO:0000313|Proteomes:UP000027898};
RN [1] {ECO:0000313|EMBL:KEF35379.1, ECO:0000313|Proteomes:UP000027898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RL {ECO:0000313|EMBL:KEF35379.1,
RC ECO:0000313|Proteomes:UP000027898};
RA Lal R., Mahato N.K., Tripathi C., Verma H., Kumari R., Singh N.;
RT "Draft genome sequence of Deinococcus sp. strain RL isolated from sediments
RT of hot springs located at Manikaran, India.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF35379.1}.
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DR EMBL; JMQF01000016; KEF35379.1; -; Genomic_DNA.
DR RefSeq; WP_034402745.1; NZ_JMQF01000016.1.
DR AlphaFoldDB; A0A072NCF6; -.
DR eggNOG; COG1253; Bacteria.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000027898; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR PANTHER; PTHR43099:SF2; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000027898};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..202
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 221..280
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 285..342
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 447 AA; 49329 MW; F2AE33A3A3C8A1BB CRC64;
MNDWLGIFAL FVLVLMNGFF VAAEFALVSV RRTRIDQLAE EGHATARVTR RALQNLDLYI
AATQLGITMA SLAIGFVAEP AIEHLLEPVF EGQGLSEAQS RTISIGIAFA LSTVLHIVIG
ELAPKSWALQ RSEQVSLLVT RPLLIFTAAF KWAIVGLNAL GNGVVRLFGL RGVAGHHAAY
SEEEIRMIVG ASSQEGVLED DEKELVYNVF DLSDTTVREI MTPRIEMVTV DGGAPLRQLL
DLNAEHGYSR VPVYQDTADN IVGIVHTGDL LAHLHELDSV RIADVMRPVF FVPEGMKIKD
LLTKMREKKS HMSIVVDEFG GTSGLVTLED ALEEIVGEIY DETDEEEQPL IEVLGEGRYL
MDASLTVGEV EERLATNLED GEGEYDTLSG FMTNHFGDIP EPGQSFVHGG WLFTVADADQ
RRVTRVRVER APETMIFETH EEPARDA
//
