ID A0A072P8J5_9EURO Unreviewed; 1339 AA.
AC A0A072P8J5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 28-JUN-2023, entry version 23.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
DE Flags: Fragment;
GN ORFNames=A1O9_12218 {ECO:0000313|EMBL:KEF51880.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF51880.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF51880.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF51880.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF51880.1}.
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DR EMBL; AMGV01000021; KEF51880.1; -; Genomic_DNA.
DR RefSeq; XP_013254470.1; XM_013399016.1.
DR STRING; 1182545.A0A072P8J5; -.
DR GeneID; 25287112; -.
DR VEuPathDB; FungiDB:A1O9_12218; -.
DR HOGENOM; CLU_002263_0_0_1; -.
DR OrthoDB; 1406366at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd17745; BRCT_p53bp1_rpt1; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR047249; BRCT_p53bp1-like_rpt1.
DR InterPro; IPR041297; Crb2_Tudor.
DR InterPro; IPR047252; TP53BP1-like.
DR PANTHER; PTHR15321:SF3; TP53-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15321; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF18115; Tudor_3; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920}.
FT DOMAIN 1076..1183
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 107..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1288..1318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KEF51880.1"
SQ SEQUENCE 1339 AA; 146803 MW; E24794BAE0F952E6 CRC64;
PDSERSTFEN PNLQAIKAYY YQLSQTSPHR PVPLQNIWPT LPSTVSDSQL LHSSIDIDSQ
FCFIPPAPPS TTNGVVTAKA PVRMSQVDDT HTQELSPSHF DSYIHKSRSA RHLEGGAGPN
DNSDNDNGLQ RHETQFTLHE GDEGHIDLIS SFEQRLEGAQ DLESEPAAGD FSPTQSGCAI
SQFPESQRFK TPATAGKKRR YNGDMVHTPY LPHNPLRQVT AQSNGNVMRL SQAFAATQAD
TSPLLHNGLV DLQSDRPSPN IELQPRPVTA ATSSPLRMLP EFTRASTEPA SRYISVKQSQ
AEREKQAEIQ RQQELAEYND DSDNGLADEQ TQIIRSRRRG GIEQRVRSTL RQLSSPSRRA
NQGPPATKSS PVRPSIQHSP IQTLLATRVG YTIVSSPPSN DVVELDNDTE VETEQEDNAD
IAVTRSSQGA VALDVEDKEN FSETGSEVPE TTARLHQILN CFSTHVQNSP SLRRSNRCTN
TSRNALDSSE PIAVANSQPS QLQRQRQIWS TSPKRAASDG IDFVPQSPTA SPQPTLEARP
LMSLHHTERE DDALATADEG PTLVDQLPTA IEPLSEDINN EISCNPHSTI PETSSNGQYV
QNNSSQPWER RNPSEGSTHN QFETAESHLP PSTNHKQPSN VVDLSSPPVN TTAPGQKRKR
LTDIAAEPSP QKSQSQLSFN ASEALQVDID LQVGPEVSTG ELLPDNPSLQ RRRAVMSPSG
ESPKKNEVSP SRADELSQTP LSRKHAGSTN TESDGPESTK KFTKRRKSYL RRDRKLSSES
LSALKANLGV KPRTPRSSVW DIIASPPQKT GPATESLKSF SALIEEPQTS SRSKQKGRRL
AKHTKKDMVS EPPATTSTET EQPSQSLEST ALNDGQCGPM TPVITDPILA PNMVFACFIG
KTRAYFPALC RGLSGGESKR FLIQWEGYDL DEIDEHGVRS LDLRVGDLVK VDLEGFPKVS
YVVRGFRHKI GPETPKAGLP FITDIRGYKT AMVAPKQRKS LPAEMSTEAV KEVPLSAIYL
DSIMWGQMKG RMFEFKLPPE NSYFPHFSPP AERTTNPSTP ISRLRRAQAT GAALVPPSGL
FANMTFAMSY DDKSRKSSLV DLVKTNGGHI VNESFQELLE PESLHLKAHF ASYTFAALLT
DSHSTKKAKY LQALALGIPC LSGKWIDACV GAGDVVDWTH YLLPAGVCFE LDGAIKSRVL
PYVSSSAAIT VRGMIDSRPN LLTGARVIVV GTGDMRKGYR FLIQALGAES VEGASNLNAA
RRLLQSNKEG DHGKNQIGYI VVNNKTDGLE DTTSSDKPTK SEKRSTPLPG PGRSKDGHFK
IISRMEIKQS LILGKLWIQ
//
