ID A0A072PDP0_9EURO Unreviewed; 696 AA.
AC A0A072PDP0;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Cryptochrome {ECO:0000313|EMBL:KEF57981.1};
GN ORFNames=A1O9_05904 {ECO:0000313|EMBL:KEF57981.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF57981.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF57981.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF57981.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC {ECO:0000256|ARBA:ARBA00005862}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF57981.1}.
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DR EMBL; AMGV01000004; KEF57981.1; -; Genomic_DNA.
DR RefSeq; XP_013260571.1; XM_013405117.1.
DR AlphaFoldDB; A0A072PDP0; -.
DR STRING; 1182545.A0A072PDP0; -.
DR GeneID; 25280824; -.
DR VEuPathDB; FungiDB:A1O9_05904; -.
DR HOGENOM; CLU_010348_3_3_1; -.
DR OrthoDB; 124765at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR Gene3D; 1.25.40.80; -; 1.
DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR InterPro; IPR006050; DNA_photolyase_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR PANTHER; PTHR11455:SF9; CRYPTOCHROME-1; 1.
DR Pfam; PF00875; DNA_photolyase; 1.
DR Pfam; PF03441; FAD_binding_7; 1.
DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW 1}; Reference proteome {ECO:0000313|Proteomes:UP000027920}.
FT DOMAIN 19..151
FT /note="Photolyase/cryptochrome alpha/beta"
FT /evidence="ECO:0000259|PROSITE:PS51645"
FT REGION 616..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..640
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 306..310
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
SQ SEQUENCE 696 AA; 78950 MW; EDDE7E6CB26DA361 CRC64;
MPPKFKSPKK QAQGAGPGPR VLYWFRTDLR LHDSPALVHA LSLEPSVFIP LWCWDPHYVY
RQRGAANRWN FLVSCMRDVS RSLTALNPKQ KLHVVRRAPG KVMVELLRRW KVDVLVFEKD
TDAYARMRDD EVRAIAEGLG VKVVSLSGRT LFDSDEVVKM NGGKPTMSMN QLVNASKKIG
DGAPKKPLDR PTSLPDPLAE AEMDLIDLDD DTGGGGEENV DYNLPQRSLG KAKNRQYDTG
IMGPKRDFGI PTLEEMGIDS ADVTSPHKGG ETAGLEALKS MMDKSDYTGT FEKPKTAPTD
FEPQATTLLS PHMHFGSVSV RKFWWDVQDV LEKRRKQNKH VSGEPVNLPG QLLFRDMYFA
AYAKLGFQFG QAVGNSVARF IPWHLQSHYV KGQKDGNPTG DGAYVVDDPQ AEEYFRRWKE
GRTGFPWIDA IMRQLKLEGW IHHLGRHAVA CFLTRGGCYV SWERGAEVFE EWLIDHEVAC
NAGNWMWLSC TAFFSQFYRV YSPIAFGKKW DPEGKFVRKY VPELAQFDKK YIYEPYKAPI
ADQKAWGCII QGDGTKTEEK GTKVFPKPMF DFNKRRQFCL DRMKEAYDVG LYGDDKRVLS
GEWKKLFDFN DKRRERKEEA NGHLPTHGTK RSKTEASDDA DRPASEDDTG ELADQGAASQ
DEEDEKPPRK AVKQTKPKKG AQKTLDTVVT TTRAKK
//
