ID A0A072PIP0_9EURO Unreviewed; 1457 AA.
AC A0A072PIP0;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=A1O9_04463 {ECO:0000313|EMBL:KEF59617.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF59617.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF59617.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF59617.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF59617.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGV01000003; KEF59617.1; -; Genomic_DNA.
DR RefSeq; XP_013262207.1; XM_013406753.1.
DR STRING; 1182545.A0A072PIP0; -.
DR GeneID; 25279394; -.
DR VEuPathDB; FungiDB:A1O9_04463; -.
DR HOGENOM; CLU_002541_1_0_1; -.
DR OrthoDB; 2788168at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd13278; PH_Bud4; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR36100; BUD SITE SELECTION PROTEIN 4; 1.
DR PANTHER; PTHR36100:SF1; BUD SITE SELECTION PROTEIN 4; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 1259..1380
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 908..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 968..987
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1088..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1404..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..237
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1457 AA; 160081 MW; 760E1B112EBCD205 CRC64;
MASEVPPLRI QKGSNGSPSK LPRVTNRPLS ELSPMAIRRN SPSFPQAKGK LFTTSESSPA
GSSPFSAASP RLFWQGRDPN SPARENSSIF DPLAPSPNKR SSIENLKKAS RVKNSSMFAI
EQSTNYDPSR PTILDGRPLS VQSLGPQSPI RTSDALRKEN FAPAKSSPGQ YTAKASQEDA
ASATTKIVSP LSPSRLNTSP AKSSLSKKTG ADFRRSGFDP ETGIWEDEDD VHNKQLPAGR
GLHRHHKSVT FDQAPPQINE YEEPTPAPSS IASESREGSC ESVEDEDEDL SFERGSSMDH
DDSFDASLED TEKTPVVLPE DWRFMSPDTA NKDLAHGEED VFDDDCGSPA PTAQPGALAY
RPHQTSAGSV DSNGQNRPLP PLPPMSLGHK KSPSDRLSGA FERMSIGQRS LPTPPMATTI
SKADIQKMGT TSSLTADDRL RLMALQEQDR ERRMRRLGSK EPTPVRAASV EDSVIVHGEP
GPELVESRES TPQISRASVL QGLRGEFSCD SRESSADTDG PHTNRRFDPD VAIPSMEDPT
HAHAQSAYIK EEDPEDQDLY SIPDAYNRRI VSESDQSANQ DDDMTSQYSQ PSVAGLPVSM
PALEDGQHTP KAQSPQTAIN SRFLTSERVS LPDFTDFGGG NDFNVGLTPY LSRKEEKLVP
PIPALSTTNV PDLAALRQSI QRSYSPDTQQ SVVPQSPVVH SFKQRSPGTP ESIVRHSVAV
KAFGRTQVND FPEVSKSDTN SDRSISPSDS GSVIVNPKEA SPVSPISTEF PENNQVPASL
SPEAVDQNAV EAKEPAQLQV PVNAKRVSSL VPLEIAHEEL DDGLGLGLEK EFDRVVEAQK
VEFELSLQRL YYPFNGRFPS NESPPQTNFA NRSNRSYILE EDSFANRSPK QQRGYLMRQN
TKIVVATERT SQDECRSPGL PTDGDANLLS PRSPANQVQA SPRKTSQPTW TAEPWNGKVR
RKSIRVGGEK ALGQRKPVSG PAPPLPGQCS NVQESLGAVA EDELGEEEDW EDGAERGRLF
VKVVGVKDLQ MPFPQHEQTY FALTLDNGLH CVTTAWLELS RSAPIGQEFE LVVLNDLEFQ
LTLQMKLEEP KVERPQSPSK PPASPKKQGA FGRLFGSPKK KKELELRAQQ EAQAVRRPVT
PPSAYELVQG LVAKDGSFAR AYVALSEHEK HTYGRPYTVD ITCFNEWALE EVQVGSSRSK
KGVVQMQRRP PYEIGKLELQ LLYVPKPRGA KDDDMPKSMN GAIRALREAE EKVQQQANIR
GFEGYLSQQG GDCPYWRRRF FKLAGPKLTA FHETTLQPRA TINLAKASRL IDDKSSLVQK
ETSTKGGGRR KSGFAEEEEG YMFVEEGFRI RFANGEVIDF YADSTADKDE WMQALAQVVG
KGVQGSSAPV KGWVEMVLKR EKKTKADGLS GSHPPRPAGH QRTETYHAGG MASHHNSPVK
SKAGREEKHR KTKSMHA
//
