ID A0A072PJP8_9EURO Unreviewed; 407 AA.
AC A0A072PJP8;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O9_04392 {ECO:0000313|EMBL:KEF59548.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF59548.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF59548.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF59548.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF59548.1}.
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DR EMBL; AMGV01000003; KEF59548.1; -; Genomic_DNA.
DR RefSeq; XP_013262138.1; XM_013406684.1.
DR AlphaFoldDB; A0A072PJP8; -.
DR STRING; 1182545.A0A072PJP8; -.
DR GeneID; 25279325; -.
DR VEuPathDB; FungiDB:A1O9_04392; -.
DR HOGENOM; CLU_034992_1_1_1; -.
DR OrthoDB; 883077at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 75..228
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 248..386
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT REGION 388..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 44150 MW; A08BA7968285D4AA CRC64;
MSPSVDHTKV TPPYARPNLH IYGFGVEYPP YDIKPEELAT LARRHYPSTP ALDKVLFVNE
YTGIDSRSAI GNIDHPIANA PDPPTIAELC DLFLDHGVKL SVAAAQKAID QWGGDLSEIT
HVVATTCTNS ANPGYDHYVV KQLGLNQSIE KVLLHGVGCS GGLAALRTAA NIALGSSFRR
KPARILVLAC EISSTLVRSE LDSIHKNQEV RIGVALFSDC ASAVVIGNGF SSRYDEEPIL
ELLDWDHRII QDTEKDLGFD VDPVGWKVVL TQRVPKLASA AVPAMFEDLV SRIPELVDQG
KFKGSDYDWA LHPGGATVIS GVEKAMHLTP EHLRASYEIY ITHGNSSSAT IFSVMQRLTE
GETTDHIVAC AFGPGIAVEM MILKRVKEGS RTGSESPTET LVAEDVD
//
