ID A0A072PPE7_9EURO Unreviewed; 575 AA.
AC A0A072PPE7;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=NCS1 family nucleobase:cation symporter-1 {ECO:0000313|EMBL:KEF57365.1};
GN ORFNames=A1O9_05282 {ECO:0000313|EMBL:KEF57365.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF57365.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF57365.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF57365.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF57365.1}.
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DR EMBL; AMGV01000004; KEF57365.1; -; Genomic_DNA.
DR RefSeq; XP_013259955.1; XM_013404501.1.
DR AlphaFoldDB; A0A072PPE7; -.
DR GeneID; 25280208; -.
DR VEuPathDB; FungiDB:A1O9_05282; -.
DR HOGENOM; CLU_021555_2_0_1; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR012681; NCS1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR NCBIfam; TIGR00800; ncs1; 1.
DR PANTHER; PTHR30618:SF2; ALLANTOIN PERMEASE-RELATED; 1.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 535..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 575 AA; 63811 MW; 36E859874740FF07 CRC64;
MSRFRGSKAS RLLGKLQTES EPGLTNAQLM LTNHDLKPVE PERRQWGPWN FVGFWVADSF
NINTWMIASS MITGSGLAWW HAWLCVWIGY FVAAVFICLT GRIGAVYHIS FPVVARSSFG
IWGSLWPVFN RAAMACIWYG VQSYIGGQCV TLMIRSIWPS FNDIHNGIPN SGTSTRDFVG
FFLFWLGSLP FIYPSVHKIR HLFTVKAYFV PAAGIAFFIW AIVRAKGIGP IVRQPAEASG
SKLAWGWISG IMASISNFAT LIVNDPDFSR FAQKPRDALW SQLFTIPIGF AVTSFIGIIV
SSSSTVIYGT AIWNPLDLLS QFLLDDASSA ERFGVFVIAT AFVLAQLGTN IAANSVSAGT
DLTALLPRYL NIRRGGYICA IVGICMCPWN LLSSSNNFTT YLSAYSVFLS SIAGVLICDY
YAVRKGYLDL KGLYSAQKSS PYFYWFGWSW RGYTAYICGI LINIVGFVDA IGTNGRMPMG
AVYLYRFNFF TGFIVSSSVY YLLCRVRPVP ATSRVWCEKP DEADRQFSVV YTEGEPYDEE
RSGGIGRGSP PAARYGAGGE EKTAAYLDKT QESRY
//
