ID A0A072U0M2_MEDTR Unreviewed; 412 AA.
AC A0A072U0M2;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=ICE-like protease (Caspase) p20 domain protein {ECO:0000313|EMBL:KEH19330.1};
DE SubName: Full=Putative Caspase-like domain-containing protein {ECO:0000313|EMBL:RHN40586.1};
GN Name=25502442 {ECO:0000313|EnsemblPlants:KEH19330};
GN OrderedLocusNames=MTR_8g447080 {ECO:0000313|EMBL:KEH19330.1};
GN ORFNames=MtrunA17_Chr8g0356311 {ECO:0000313|EMBL:RHN40586.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH19330.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH19330.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH19330.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH19330,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH19330.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH19330.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH19330,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH19330}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH19330};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [4] {ECO:0000313|EMBL:RHN40586.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN40586.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the peptidase C14B family.
CC {ECO:0000256|ARBA:ARBA00009005}.
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DR EMBL; CM001224; KEH19330.1; -; Genomic_DNA.
DR EMBL; PSQE01000008; RHN40586.1; -; Genomic_DNA.
DR RefSeq; XP_013445304.1; XM_013589850.1.
DR AlphaFoldDB; A0A072U0M2; -.
DR EnsemblPlants; KEH19330; KEH19330; MTR_8g447080.
DR GeneID; 25502442; -.
DR Gramene; KEH19330; KEH19330; MTR_8g447080.
DR KEGG; mtr:25502442; -.
DR HOGENOM; CLU_029389_4_1_1; -.
DR OrthoDB; 670122at2759; -.
DR Proteomes; UP000002051; Chromosome 8.
DR Proteomes; UP000265566; Chromosome 8.
DR ExpressionAtlas; A0A072U0M2; differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR Gene3D; 3.40.50.12660; -; 2.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR PANTHER; PTHR48104; METACASPASE-4; 1.
DR PANTHER; PTHR48104:SF50; METACASPASE-4; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KEH19330.1};
KW Protease {ECO:0000313|EMBL:KEH19330.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051}.
FT DOMAIN 3..402
FT /note="Peptidase C14 caspase"
FT /evidence="ECO:0000259|Pfam:PF00656"
FT REGION 186..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..208
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 44919 MW; E755038CEC88C6AA CRC64;
MARKAVLIGI NYPGTKAELR GCVNDVWRMH KCLIERYGFS EDDITILIDT DSSYTEPTGK
NIRRVLSELV RSSEDGDVLF VHYSGHGTRL PAETGEDDDT GFDECIVPSD MNLITDDDFK
EFVDGVPRGC RLTIVSDSCH SGGLIEEAKE QIGESTKGEE EHSGSGFGLS GFLHRKVEDA
IESRGFHVPS GLRSHTRRDE ETNEDRDIEL PHGVKNRSLP LSTLIDILKQ KTGKEDIDVG
QLRPTLFDVF GEDASPKVKK FMKVILNKLQ HGGGEGGQGG ILGMVGSLAQ EFLKQKLNDN
DEGYAKPAME TEVGSKHEVY AGSSKRGLPS GGILMSGCQT DQTSADACPS GNAANAYGAF
SNAIQAIIEE TDGAITYSEL ILKAREKLQK DGFTQKPGLY CSDHHVDDPF LC
//
