ID A0A072U238_MEDTR Unreviewed; 1358 AA.
AC A0A072U238;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Regulatory-associated protein of TOR protein {ECO:0000313|EMBL:KEH23253.1};
GN Name=11428688 {ECO:0000313|EnsemblPlants:KEH23253};
GN OrderedLocusNames=MTR_7g072330 {ECO:0000313|EMBL:KEH23253.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH23253.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH23253.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH23253.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH23253,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH23253.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH23253.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH23253,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH23253}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH23253};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC {ECO:0000256|ARBA:ARBA00009257}.
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DR EMBL; CM001223; KEH23253.1; -; Genomic_DNA.
DR RefSeq; XP_013449226.1; XM_013593772.1.
DR EnsemblPlants; KEH23253; KEH23253; MTR_7g072330.
DR GeneID; 11428688; -.
DR Gramene; KEH23253; KEH23253; MTR_7g072330.
DR HOGENOM; CLU_001136_3_0_1; -.
DR OrthoDB; 103066at2759; -.
DR Proteomes; UP000002051; Chromosome 7.
DR ExpressionAtlas; A0A072U238; differential.
DR GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR004083; Raptor.
DR InterPro; IPR029347; Raptor_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR Pfam; PF14538; Raptor_N; 1.
DR Pfam; PF00400; WD40; 2.
DR PRINTS; PR01547; YEAST176DUF.
DR SMART; SM01302; Raptor_N; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 121..274
FT /note="Raptor N-terminal CASPase-like"
FT /evidence="ECO:0000259|SMART:SM01302"
FT REPEAT 1098..1115
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 809..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1358 AA; 149176 MW; FE75CCBA4F4019FD CRC64;
MALGDLMASR FSQSTVLIVP NHHRDDSTST TAFSASASSA SAAALNDDGS DFNSSVPNRR
DSEFGAASSS SAGVYGNAAT TMVYLPQTSF FNELRHDAFE LELPTGPSDS GLVSKWRPKD
RMKTGCVALV LCLNINVDPP DVIKISPCAR MECWIDPFSM APQKALELIG KSLTSQYERW
QPKARYKCQL DPTLDEVKKL CTTCRRYAKS ERVLFHYNGH GVPKPTHNGE LWVFNKSYTQ
YIPLPLNDLD SWLKTPSIYV FDCSAAGKVV NAFIQLHEWN ASNSDGSPRD CIMLAACEAH
ETLPQSVEFP ADVFTACLTT PIKMALRWFS TRSLLRDSFD YLLIDKIPGR PNDRKTLLGE
LNWIFTAVTD TIAWNVLPHD LFQRLFRQDL LVASLFRNFL LAERIMRSAN CTPVSHPMLP
PTHQHHMWDA WDMAAELCLS QLPSLVEDPN AEFQPSTFFT EQLTAFEVWL DHGSEHKKPP
EQLPIVLQVL LSQCHRFRAL VLLGRFLDMG PWAVDLALSV GIFPYVLKLL QTTTPELRQI
LVFIWTKILA LDKSCQVDLV KDGGHIYFMK FLDSSEAYPE QRAMAAFVLA VIVDGHRRGQ
EACIEAGLSH VCLKHLESSS PNDSQTEPLF LQWLCLCLGK LWEEFPEGKI IGLQGHATSI
LAPLLSEPQP EVRASAVFAL GTLVDVGFDS CRSVGDEECD DDDKFRAEVS IVRSLLSVAS
DGSPLVRAEV AVALARFAFG HNKHLKSIAA AYWKPQTNSL INSLPSLTNI KDTGGGYSKQ
NQHMAHGSIV SPQIGPLRVG SDNSKVIRDG RVSSSSPLAS SGIMHGSPLS DNSSHHSDSG
ILNDGFSNGV VNSFGPKPLD NALYSQCVLA MCTLAKDPSP RVGNLGRRVL SIIGIEQVVA
KPLKPSGVRT SSVVPVSASL ARSSSWFDMN GVSPPRPSYI AGMRRVCSLE FRPHLMTSPD
TGLADPLLGS GTFDRSLLPQ SSIYNWSCGH FSKSLLTAAD DSEEVLARRE EREKFALEHI
VKCQHSAVSR LTNPIAKWDI KGTQTLLLQP FSPIVVAADE NERIRVWNHE EATLLNSFDN
HDFPDKGISK LCLVNELDDS LLLAASSDGN VRVWKDYSLR GKQKLVTAFS SIHGHKPGVR
SPNAVVDWQQ QCGYLYASGE TSLIMMWDLD KEQLVNTIPS SSECSVSALA ASQVHGGQFA
AGFVDGSVRL YDARTPEMLV CGLRPHTQRV EKVMGIGFQP GLDPGKLVSA SQAGDIQFLD
IRNHSSAYLT IEAHRGSLTA LAVHRHAPII ASGSAKQLIK VFSLEGDQLG TIRYYPTLMA
QKIGSVSCLS FHPYQLLLAA GAADACVCIY ADDNTQAK
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