ID A0A072U2Z3_MEDTR Unreviewed; 876 AA.
AC A0A072U2Z3;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Transcription regulator NOT2/NOT3/NOT5 family protein {ECO:0000313|EMBL:KEH23518.1};
GN Name=11437872 {ECO:0000313|EnsemblPlants:KEH23518};
GN OrderedLocusNames=MTR_7g085350 {ECO:0000313|EMBL:KEH23518.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH23518.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH23518.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH23518.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH23518,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH23518.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH23518.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH23518,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH23518}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH23518};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682}.
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DR EMBL; CM001223; KEH23518.1; -; Genomic_DNA.
DR RefSeq; XP_013449490.1; XM_013594036.1.
DR AlphaFoldDB; A0A072U2Z3; -.
DR EnsemblPlants; KEH23518; KEH23518; MTR_7g085350.
DR GeneID; 11437872; -.
DR Gramene; KEH23518; KEH23518; MTR_7g085350.
DR OrthoDB; 10289at2759; -.
DR Proteomes; UP000002051; Chromosome 7.
DR ExpressionAtlas; A0A072U2Z3; differential.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.1020; CCR4-NOT complex subunit 2/3/5, C-terminal domain; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_C_sf.
DR InterPro; IPR012270; CCR4-NOT_su3/5.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007282; NOT2/3/5_C.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04153; NOT2_3_5_C; 1.
DR Pfam; PF04065; Not3; 1.
DR PIRSF; PIRSF005290; NOT_su_3_5; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..236
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT DOMAIN 733..871
FT /note="NOT2/NOT3/NOT5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04153"
FT REGION 110..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 132..159
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 357..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 876 AA; 96287 MW; ED7AA33FC8DF28EA CRC64;
MGASRKLQGE IDRVLKKVQE GVEVFDSIWN KVYDTDNANQ KEKFEADLKK EIKKLQRYRD
QIKTWIQSSE IKDKKVSASY EQALVDARKL IEREMERFKI CEKETKTKAF SKEGLGQQPK
TDPREKAKSE TRDWLNNVVG ELESQIDNFE AELEGLTVKK GKNRPSRLTH LETSITRHKA
HIKKCELVLR LLDNDELSPE EVNDVKDFLD DYVERNQDDF DEFDDVDELY SSLPLDKVDT
LEDLVTIPTS VAVAKVAPGL SLKTPLAASA SQSASSQTSE QADETASQDS NSDIVAKTPP
PKSGGISSST STPTGNHATP ASVNVSGLNL SSAPAAAILP GSNSVRNILE NAIVNQSTSP
KEEEINNFPT RRPSPSLSDA ALVRGRNSLS NQATASIPLG SGNTVSSIGA LGVVPSASEI
TKRNILGADD RLGSSGMVQP LVSPLSNRLI LPQIGKANDG AASVDSSIVN EAAAVSGRVF
SPSVVPGMQW RPGSPFQNQN DAGQLRGRTE IAPDQREKFL QKFQQVQQQG PSTLLNMPSL
VGGNHKQFSS QQQSPLLQQF NSQGSSVSSQ SSMGLGAQSP SLGGISSVSL QQLNSVHSPS
GQHPFAGVAK DADKFEEHQQ HQNFPDESTT ESTSSTGIGK NLTVEDDLKS AYALDSPAGL
SASLPEAAQT FRDIDLSPGQ PLQSNQSTGN LGVIGRRNGV ELGAIGDSFG ASSVNSGGVR
DQLYNLQMLE AAHFRMPQPR DSERPRTYTP RHPAITPSSY PQVQAPIVNN PAFWERLGLE
PFGTDTLFFA FYYQQNTYQQ YLAAKELKKQ SWRYHRKYNT WFQRHEEPKV ATDDYEQGTY
VYFDFHIAND DLQHGWCQRI KNDFTFEYNY LEDELV
//
