ID A0A072UIM5_MEDTR Unreviewed; 969 AA.
AC A0A072UIM5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Verticillium wilt disease resistance protein {ECO:0000313|EMBL:KEH28923.1};
GN OrderedLocusNames=MTR_4g017730 {ECO:0000313|EMBL:KEH28923.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH28923.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH28923.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH28923.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH28923,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH28923.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH28923.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH28923,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH28923}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH28923};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000256|ARBA:ARBA00009592}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001220; KEH28923.1; -; Genomic_DNA.
DR RefSeq; XP_013454875.1; XM_013599421.1.
DR AlphaFoldDB; A0A072UIM5; -.
DR STRING; 3880.A0A072UIM5; -.
DR EnsemblPlants; KEH28923; KEH28923; MTR_4g017730.
DR Gramene; KEH28923; KEH28923; MTR_4g017730.
DR HOGENOM; CLU_000288_18_3_1; -.
DR Proteomes; UP000002051; Chromosome 4.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR046956; RLP23-like.
DR PANTHER; PTHR48061; LEUCINE-RICH REPEAT RECEPTOR PROTEIN KINASE EMS1-LIKE-RELATED; 1.
DR PANTHER; PTHR48061:SF2; LEUCINE-RICH REPEAT-CONTAINING N-TERMINAL PLANT-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 6.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF08263; LRRNT_2; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 6.
DR SUPFAM; SSF52058; L domain-like; 3.
DR PROSITE; PS51450; LRR; 2.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 908..929
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..28
FT /note="Leucine-rich repeat-containing N-terminal plant-
FT type"
FT /evidence="ECO:0000259|Pfam:PF08263"
SQ SEQUENCE 969 AA; 108051 MW; CD24C0EB5BF92987 CRC64;
MFKPEISNKL KLWNSSVDGC EWIGVACDSK GFVVGLDLSE ESISGGFDNA SSLFSLQHLQ
KLNLAANNFN SVIPSGFNKL VMLSYLNLSY ANFVGQIPIE ISQLTRLVTL DISSVNSYIT
GQGLKLEKPN LQKFVQNLTS LRKLYLDGVS IKAQGQEWRN ALLPLPNLQV LSMSYCDLSG
PLDSSLTRLK NLSVIILDGN NFSSPVPQTF SNFKKLTTLS LASCGLTGKF PKTIFQIGTF
SFIDLSFNYN LHGSIPEFLL GGSLQTLRIR NTSFSGAFPY SIGNMGHLSE LDLSNCELNG
TLPFSLSNLT KLRYMDLSSN SFTGQMPPFG MAKNLTRLNL SHNRLSGEIS SSNHFEGLHN
LVSVDLRDNF INGSIPSSLF ALTLLLNIQL SLNQFSKFDK LINVSTSVLK TLDLSNNDLS
GPFPMSIFKL HSLSVLDLSF NRLNGSLQLD ELMELRDLST LDLSYNNISV NIQGIVPNWI
WRIQNLQSLN ISHNMLTGFD GPLHNLTSNL ISLDLHNNQL QGPIPVFSEF SSYLDYSMNK
FDSVIPQDIG NYLSFTTFLS FSNNTLHGTI PRSLCNASNL QVLDISINSI SGTIPSCLML
MTQTLVVLNL KMNNLIGTIP DVFPPYCVLR TLDLQKNNLD GQIPKSLVKC SALEVLNLAN
NIIIGTFPCL LKNISTIRVI VLRSNKFNGH IGCPNTSGTW QMLQIVDLAF NNFSGKLPGK
FFTTWEAMRS DENQADLKVK RVQFEVLQFG QIYYHDSVTV TSKGQQMDLV KILTVFTSID
FSSNHFEGPI PYSIGNFKAL YILNISNNRL SGKIPSSIGN LKQLESLDLS NNTLTGEIPV
QLESLSFLSY LNLSFNHLVG KIPTGTQLQS FQSSSFEGND GLYGPPLTEK PDGKRNDELL
SCSTDWKFLS VELGFVFGLG IVIGPLMFWK QWRIRYWKLV DKILCWIFSR IHLEYVTHRG
QTYIVLRWH
//
