ID A0A072UL87_MEDTR Unreviewed; 940 AA.
AC A0A072UL87;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=NBS-LRR type disease resistance protein {ECO:0000313|EMBL:KEH30519.1};
GN Name=25492796 {ECO:0000313|EnsemblPlants:KEH30519};
GN OrderedLocusNames=MTR_4g073840 {ECO:0000313|EMBL:KEH30519.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH30519.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH30519.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH30519.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH30519,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH30519.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH30519.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH30519,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH30519}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH30519};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
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DR EMBL; CM001220; KEH30519.1; -; Genomic_DNA.
DR RefSeq; XP_013456488.1; XM_013601034.1.
DR AlphaFoldDB; A0A072UL87; -.
DR STRING; 3880.A0A072UL87; -.
DR EnsemblPlants; KEH30519; KEH30519; MTR_4g073840.
DR GeneID; 25492796; -.
DR Gramene; KEH30519; KEH30519; MTR_4g073840.
DR KEGG; mtr:25492796; -.
DR HOGENOM; CLU_000837_25_4_1; -.
DR OrthoDB; 905141at2759; -.
DR Proteomes; UP000002051; Chromosome 4.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1193; DISEASE RESISTANCE PROTEIN RPP13-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051}.
FT DOMAIN 5..88
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 174..435
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 251..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 940 AA; 108131 MW; 653A665905421C58 CRC64;
MADSVVAFLL EHLSQLLQHE ANLLCGVQDR IISLRNELEI INAYLKTSSR GNRNNNKEIE
QKVLSQIRDV AHVAEDVIDT FIANIAMYKK RNMLGRMLHS VDHAKLLHDV AEKIDKIKTT
LNEIHENRIK YYQESSDQSS SAREEEERIQ SLHRLRRNVE EENVVGFVHE SEVVINRLIV
DDSSSPRLKV VSIIGMGGLG KTTLARKIYN SEEVKNHFDC RAWVYVSNEC RSRELLLGLL
QNLMPNHINN DCRSSSSNIK KKGKKKHKEG VNNSQDISSL SNDELKKKVW ECFKWKKYLL
VLDDLWKIQD WDEVKDAFPD GNRGSRILIT SRLKEVASHT GRDPPYCLQF LTEEHSWELF
SKKVFRGEKY PCDLESLGKQ IVKSCGGLPL SILVLAGLLA NKEKSHREWS KLLGHVNWYL
TRDETQVKDI VLKLSFNDLP SRLKPCFLYL GIFPEDYEIC VRQLLQLWVA EGFIQETGNR
DPNDVAEDYL YELIDRSLIQ VAQVKDSGGV KTCRIHDLLR DLCILESKED KIFQICTDSN
ILIPTKPRRL SVHSTMSHYV SSSTNDHSCV RSLFCSDPNC FVYSDEWKWL TKGFKLVRVL
DLDGKYCFKI PSNLGNFVHL RYLRIDSHYI RSVPDSICSL QNLQTLYLGP SIRVTTISFP
CGITKLKHIR HLYTCGPIKL RGDCSESNGD AMWNLQTISS IVLDKRTTYL IEKGSFPKLR
KLCLQISSNF KGDVPKMLIS LQHLRHLNKL EIYFQVKDWP HSRWEINCKA EEVLQSLKHL
RHLSILKIRN ALDLFTCVAM FPPNITKLTL SCISCLNDDG INAIGNLTKL QILILTGDNW
FLDFWPSDSL FDINCIEDGF PQLKEFQMGN LPVRNWKLAN GSMSRLQILV IHHCDKFDSL
PSELWSLTTL RKVCVRKPSD AMAAMLQNLE VKNGCELIVE
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